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Recombinant Human COL4A3BP, His-tagged

Cat.No. : COL4A3BP-26193TH
Product Overview : Recombinant fragment, corresponding to amino acids 347-598 of Human COL4A3BP with N terminal His tag; 290aa with tag, 33.1kDa.
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  • Gene Information
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Description : This gene encodes a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport. Three transcript variants encoding different isoforms have been found for this gene.
Protein length : 252 amino acids
Conjugation : HIS
Molecular Weight : 33.100kDa inclusive of tags
Source : E. coli
Tissue specificity : Widely expressed.
Form : Liquid
Purity : >95% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, pH 8.0
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids : MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWAGSMLH WPTSLPSGDA FSSVGTHRFV QKVEEMVQNH MTYSLQDVGG DANWQLVVEE GEMKVYRREV EENGIVLDPL KATHAVKGVT GHEVCNYFWN VDVRNDWETT IENFHVVETL ADNAIIIYQT HKRVWPASQR DVLYLSVIRK IPALTENDPE TWIVCNFSVD HDSAPLNNRC VRAKINVAMI CQTLVSPPEG NQEISRDNIL CKITYVANVN PGGWAPASVL RAVAKREYPK FLKRFTSYVQ EKTAGKPILF
Sequence Similarities : Contains 1 PH domain.Contains 1 START domain.
Gene Name : COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein [ Homo sapiens ]
Official Symbol : COL4A3BP
Synonyms : COL4A3BP; collagen, type IV, alpha 3 (Goodpasture antigen) binding protein; collagen type IV alpha-3-binding protein; ceramide transporter; CERT; GPBP; StAR related lipid transfer (START) domain containing 11; STARD11;
Gene ID : 10087
mRNA Refseq : NM_001130105
Protein Refseq : NP_001123577
MIM : 604677
Uniprot ID : Q9Y5P4
Chromosome Location : 5q13.3
Pathway : Metabolism of lipids and lipoproteins, organism-specific biosystem; Sphingolipid metabolism, organism-specific biosystem;
Function : ceramide binding; phosphatidylinositol-4-phosphate binding; protein binding; protein kinase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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