Recombinant Human CSF2RB, Fc-tagged

• Cat.No.: CSF2RB-29794TH
• Product Overview: Recombinant full length extracellular domain of Human IL3RB fused to the Fc region of Human IgG1 expressed in modified Human 293 cells.

Specification

• Description: The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP).
• Conjugation: Fc
• Form: Lyophilised:It is recommended that 0.5 ml of sterile phosphate-buffered saline be added to the vial.Following reconstitution short-term storage at 4°C is recommended, with longer-term storage in aliquots at -18 to -20°C. Repeated freeze thawing is not rec
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 10% Trehalose, 1% Human serum albumin, PBS
• Storage: Store at +4°C.
• Sequences of amino acids: Theoretical Sequence:WERSLAGAEETIPLQTLRCYNDYTS HITC RWADTQDAQRLVNVTLIRRVNEDLL EPVSCDLSDDMPW SACPHPRCVPRRCVIPCQSFVVTDV DYFSFQPDRPLGTRLTVTLTQHVQP PEPRDLQISTDQDHFLLTWSVALGS PQS HWLSPGDLEFEVVYKRLQDSWEDAA ILLSNTSQATLGP EHLMPSSTYVARVRTRLAPGSRLSG RPSKWSPEVCWDS QPGDEAQPQNLECFFDGAAVLSCSW EVRKEVASSVSFGLFYKPSPDAGEE ECSPVLREGLGSLHTRHHCQIPVPD PAT HGQYIVSVQPRRAEKHIKSSVNIQM APPSLNVTKDGDS YSLRWETMKMRYEHIDHTFEIQYRK DTATWKDSKTETL QNAHSMALPALEPSTRYWARVRVRT SRTGYNGIWSEWSEA RSWDTESVLPMWGSSNTKVDKKVEP KSCDKTHTCPPCP APELLGGPSVFLFPPKPKDTLMISR TPEVTCVVVDVSH EDPEVKFNWYVDGVEVHNAKTKPRE EQYNSTYRVVSVL TVLHQDWLNGKEYKCKVSNKALPAP IEKTISKAKGQPREP QVYTLPPSRDELTKNQVSLTCLVKG FYPSDIAVEWESN GQPENNYKTTPPVLDSDGSFFLYSK LTVDKSRWQQGNV FSCSVMHEALHNHYTQKSLSLSPGK
• Sequence Similarities: Belongs to the type I cytokine receptor family. Type 4 subfamily.Contains 2 fibronectin type-III domains.

Gene Information

• Gene Name: CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) [ Homo sapiens ]
• Official Symbol: CSF2RB
• Synonyms: CSF2RB; colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage); IL3RB; cytokine receptor common subunit beta; CD131; IL5RB
• Gene ID: 1439
• mRNA Refseq: NM_000395
• Protein Refseq: NP_000386
• MIM: 138981
• Uniprot ID: P32927
• Chromosome Location: 22q12.2-q13.1
• Pathway: Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem
• Function: cytokine receptor activity; contributes_to interleukin-3 receptor activity; contributes_to interleukin-5 receptor activity; protein binding; receptor activity