Recombinant Human CTNNA2, His-tagged

• Cat.No.: CTNNA2-27148TH
• Product Overview: Recombinant fragment, corresponding to amino acids 681-905 of Human alpha 2 Catenin isoform 2, with N terminal His tag, 225aa, MWt 26kDa,

Specification

• Description: It has been shown that alpha N-catenin, a linker between cadherin adhesion receptors and the actin cytoskeleton, is essential for stabilizing dendritic spines in rodent hippocampal neurons in culture.
• Conjugation: HIS
• Source: E. coli
• Form: Lyophilised:Reconstitution with 80 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: AKIAEQVEIFHQEKSKLDAEVAKWDDSGNDIIVLAKQMCM IMMEMTDFTRGKGPLKNTSDVINAAKKIAEAGSRMDKL ARAVADQCPDSACKQDLLAYLQRIALYCHQLNICSKVK AEVQNLGGELIVSGLDSATSLIQAAKNLMNAVVLTVKA SYVASTKYQKVYGTAAVNSPVVSWKMKAPEKKPLVKREKP EEFQTRVRRGSQKKHISPVQALSEFKAMDSF

Gene Information

• Gene Name: CTNNA2 catenin (cadherin-associated protein), alpha 2 [ Homo sapiens ]
• Official Symbol: CTNNA2
• Synonyms: CTNNA2; catenin (cadherin-associated protein), alpha 2; catenin alpha-2; cadherin associated protein; related; cancer/testis antigen 114; CAP R; CT114
• Gene ID: 1496
• mRNA Refseq: NM_004389
• Protein Refseq: NP_004380
• MIM: 114025
• Uniprot ID: P26232
• Chromosome Location: 2p12-p11.1
• Pathway: Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Bacterial invasion of epithelial cells, organism-specific biosystem
• Function: cadherin binding; protein binding; structural constituent of cytoskeleton