Address: 45-1 Ramsey Road, Shirley, NY 11967, USA    USA: 1-631-559-9269  1-631-448-7888   Fax: 1-631-938-8127  Europe: 44-207-097-1828   Email: info@creative-biomart.com
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Native Human CTSD

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GST(1)
GST-His(1)
His(10)
N/A(3)
Cat.No.:
CTSD-27858TH
Product Overview:
Full length native mature Cathepsin D protein purified from Human liver.
Description:
This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease.
Biological activity:
Specific activity:541 Units/mg (prior to lyophilization).One unit is the amount of enzyme which digests hemoglobin releasing peptides which are soluble in 10% TCA.The reaction is measured by an increase of an A280 of 1.0 per 60 minutes at 37oC.Substrate:
Form:
Lyophilised:Reconstitute with 28.3ul distilled water. Protein: 0.883mg/ml (prior to lyophilization).
Purity:
>95% by SDS-PAGE
Storage buffer:
Preservative: NoneConstituents: 2mM Sodium phosphate, pH 6.5
Storage:
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sequence Similarities:
Belongs to the peptidase A1 family.


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Note: There will be extra charge for optional service!
Optional requirements on this protein +Expand
C-fusion   N-fusion  Non-tagged
His   GST  Fc  Others
<1.0 eu/μg   <0.1 eu/μg  <0.01 eu/μg  Not required
Monomer Isolation   Dimer Isolation   Not required
>80% by SDS-PAGE   >90% by SDS-PAGE  >95% by SDS-PAGE  Others
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45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-097-1828
FAX: 1-631-938-8127
EMAIL: info@creative-biomart.com

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