Native Human CTSS

• Cat.No.: CTSS-27405TH
• Product Overview: Full length native Human Cathepsin S purified from Human Spleen; amino acids 115-331, 217 amino acids, MWt 24 kDa.

Specification

• Description: The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. The encoded protein can function as an elastase over a broad pH range in alveolar macrophages. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
• Biological activity: Activity: Cathepsin S activity detected using Z-Val-Val-Arg-AMC
• Form: Lyophilised
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 100mM Sodium acetate, 1mM EDTA, pH 5.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Gene Information

• Gene Name: CTSS cathepsin S [ Homo sapiens ]
• Official Symbol: CTSS
• Synonyms: CTSS; cathepsin S
• Gene ID: 1520
• mRNA Refseq: NM_001199739
• Protein Refseq: NP_001186668
• MIM: 116845
• Uniprot ID: P25774
• Chromosome Location: 1q21
• Pathway: Adaptive Immune System, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Antigen processing-Cross presentation, organism-specific biosystem; Class I MHC mediated antigen processing &
• Function: cysteine-type endopeptidase activity; peptidase activity