Recombinant Human CTSZ

• Cat.No.: CTSZ-27236TH
• Product Overview: Recombinant full length Human Cathepsin Z with a N terminal proprietary tag. Predicted MW 59.40kDa

Specification

• Description: The protein encoded by this gene is a lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. The encoded protein has also been known as cathepsin X and cathepsin P. This gene is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis.
• Protein length: 303 amino acids
• Molecular Weight: 59.400kDa inclusive of tags
• Source: Wheat germ
• Tissue specificity: Widely expressed.
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGD GLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDGVNYASIT RNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSV QNVIDCGNAGSCEGGNDLSVWDYAHQHGIPDETCNNYQAK DQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGRE KMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYIN HVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRIVTSTY KDGKGARYNLAIEEHCTFGDPIV
• Sequence Similarities: Belongs to the peptidase C1 family.

Gene Information

• Gene Name: CTSZ cathepsin Z [ Homo sapiens ]
• Official Symbol: CTSZ
• Synonyms: CTSZ; cathepsin Z; CTSX
• Gene ID: 1522
• mRNA Refseq: NM_001336
• Protein Refseq: NP_001327
• MIM: 603169
• Uniprot ID: Q9UBR2
• Chromosome Location: 20q13.32
• Pathway: Clathrin derived vesicle budding, organism-specific biosystem; Lysosome, organism-specific biosystem; Lysosome, conserved biosystem; Lysosome Vesicle Biogenesis, organism-specific biosystem; Membrane Trafficking, organism-specific biosystem
• Function: cysteine-type endopeptidase activity; cysteine-type peptidase activity; peptidase activity