Recombinant Human DECR1, His-tagged
Cat.No. : | DECR1-26259TH |
Product Overview : | Recombinant full length Human DECR1 with N terminal His tag; 322 amino acids with tag, MWt 34.4 kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes an accessory enzyme which participates in the beta-oxidation and metabolism of unsaturated fatty enoyl-CoA esters. |
Protein length : | 301 amino acids |
Conjugation : | HIS |
Molecular Weight : | 34.400kDa inclusive of tags |
Source : | E. coli |
Tissue specificity : | Heart = liver = pancreas >kidney >>skeletal muscle = lung. |
Form : | Liquid |
Purity : | >90% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0 |
Storage : | Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequences of amino acids : | MGSSHHHHHHSSGLVPRGSHM NTEALQSKFFSPLQKAMLPPNSFQG KVAFITGGGTGLGKGMTTLLSSLGA QCVIASRKMDVLKATAEQISSQTGN KVHAIQCDVRDPDMVQNTVSELIKV AGHPNIVINNAAGNFISPTERLSPN AWKTITDIVLNGTAFVTLEIGKQLI KAQKGAAFLSITTIYAETGSGFVVP SASAKAGVEAMSKSLAAEWGKYGMR FNVIQPGPIKTKGAFSRLDPTGTFE KEMIGRIPCGRLGTVEELANLAAFL CSDYASWINGAVIKFDGGEEVLISG EFNDLRKVTKEQWDTIEELIRKTKG S |
Sequence Similarities : | Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily. |
Gene Name : | DECR1 2,4-dienoyl CoA reductase 1, mitochondrial [ Homo sapiens ] |
Official Symbol : | DECR1 |
Synonyms : | DECR1; 2,4-dienoyl CoA reductase 1, mitochondrial; DECR; 2,4-dienoyl-CoA reductase, mitochondrial; SDR18C1; short chain dehydrogenase/reductase family 18C; member 1; |
Gene ID : | 1666 |
mRNA Refseq : | NM_001359 |
Protein Refseq : | NP_001350 |
Uniprot ID : | Q16698 |
Chromosome Location : | 8q21.3 |
Pathway : | Fatty Acid Beta Oxidation, organism-specific biosystem; Fatty Acid Biosynthesis, organism-specific biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Mitochondrial Fatty Acid Beta-Oxidation, organism-specific biosystem; |
Function : | 2,4-dienoyl-CoA reductase (NADPH) activity; 2,4-dienoyl-CoA reductase (NADPH) activity; NADPH binding; nucleotide binding; oxidoreductase activity, acting on NADH or NADPH; |
Products Types
◆ Recombinant Protein | ||
DECR1-205C | Recombinant Cynomolgus Monkey DECR1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Decr1-2516M | Recombinant Mouse Decr1 Protein, Myc/DDK-tagged | +Inquiry |
DECR1-459C | Recombinant Cynomolgus DECR1 Protein, His-tagged | +Inquiry |
DECR1-26H | Recombinant Human DECR1 protein, MYC/DDK-tagged | +Inquiry |
DECR1-576Z | Recombinant Zebrafish DECR1 | +Inquiry |
◆ Lysates | ||
DECR1-6997HCL | Recombinant Human DECR1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionDECR1 works alongside other enzymes in β-oxidation, ensuring effective fatty acid degradation.
DECR1 plays a role in energy production by aiding in the efficient processing of fatty acids in mitochondria.
Mutations in DECR1 can impact fatty acid metabolism, potentially leading to metabolic disorders.
It specifically catalyzes the reduction of double bonds in unsaturated fatty acids, facilitating their breakdown.
Altered DECR1 activity can affect energy balance and fat metabolism, influencing conditions like diabetes and obesity.
Targeting DECR1 could offer new treatment avenues for managing metabolic conditions like obesity and diabetes.
DECR1, or 2,4-dienoyl-CoA reductase 1, is key in the metabolism of unsaturated fatty acids, particularly in β-oxidation.
Customer Reviews (3)
Write a reviewInvaluable support. Crucial for protein experiments.
Key to credibility. Enhances research credibility.
Swift and accurate. An asset to our research.
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