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Recombinant Human DGKZ, His-tagged

Cat.No. : DGKZ-26682TH
Product Overview : Recombinant fragment, corresponding to amino acids 641-895 of Human DGKZ with N terminal His tag; MWt 35kDa.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and multiple transcript variants encoding distinct isoforms have been identified.
Conjugation : HIS
Source : E. coli
Tissue specificity : Highest levels in brain, and substantial levels in skeletal muscle, heart, and pancreas. Isoform 1 is predominantly expressed in muscle.
Form : Lyophilised:Reconstitute with 148 μl aqua dest.
Storage buffer : Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
Storage : Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : GTVVVPGDSDLELCRAHIERLQQEP DGAGAKSPTCQKLSP KWCFLDATTASRFYRIDRAQEHLNY VTEIAQDEIYILD PELLGASARPDLPTPTSPLPTSPCS PTPRSLQGDAAPP QGEELIEAAKRNDFCKLQELHRAGG DLMHRDEQSRTLL HHAVSTGSKDVVRYLLDHAPPEILD AVEENGETCLHQAAALGQRTICHYI VEAGASLMKTDQQGDTPRQRAEKAQ DTE LAAYLENRQHYQMIQREDQETAV
Sequence Similarities : Belongs to the eukaryotic diacylglycerol kinase family.Contains 2 ANK repeats.Contains 1 DAGKc domain.Contains 2 phorbol-ester/DAG-type zinc fingers.
Gene Name : DGKZ diacylglycerol kinase, zeta [ Homo sapiens ]
Official Symbol : DGKZ
Synonyms : DGKZ; diacylglycerol kinase, zeta; diacylglycerol kinase, zeta 104kDa; diacylglycerol kinase zeta; DAGK5; DAGK6; DGK ZETA; hDGKzeta;
Gene ID : 8525
mRNA Refseq : NM_001199267
Protein Refseq : NP_001186196
MIM : 601441
Uniprot ID : Q13574
Chromosome Location : 11p11.2
Pathway : Effects of PIP2 hydrolysis, organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Glycerolipid metabolism, organism-specific biosystem; Glycerolipid metabolism, conserved biosystem;
Function : ATP binding; diacylglycerol kinase activity; diacylglycerol kinase activity; enzyme inhibitor activity; lipid kinase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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