Recombinant Mouse Bone Morphogenetic Protein Receptor, Type 1A
Cat.No. : | Bmpr1a-1709M |
- Specification
- Gene Information
- Related Products
Cat. No. : | Bmpr1a-1709M |
Description : | Cellular responses to bone morphogenetic proteins (BMPs) have been shown to be mediated by the formation of hetero-oligomeric complexes of the type I and type II serine/threonine kinase receptors. BMP receptor 1A (BMPR-1A), also known as activin receptor-like kinase (ALK)-3, is a monomeric glycoprotein and is a one of seven known type I serine/threonine kinases that are required for the signal transduction of TGF-β family cytokines. Human and mouse BMPR-IA are highly conserved and share 98% sequence identity. BMPRIA immunohistochemistry may be a promising new tool for the identification of enteric ganglion cells in the evaluation of patients with neurointestinal disorders. |
Molecular Weight : | The predicted molecular weight of Recombinant Mouse BMPR-IA is Mr 41.5 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 55 kDa. |
Source : | Mammalian cells |
State Of Matter : | Lyophilized. |
Purity : | >95% by SDS Page and analyzed by silver stain. |
Endotoxin : | <1.0 EU/µg as determined by the LAL method. |
Storage And Stability : | This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. |
Gene Name : | Bmpr1a bone morphogenetic protein receptor, type 1A [ Mus musculus ] |
Synonyms : | Bmpr1a; bone morphogenetic protein receptor, type 1A; ALK3; Bmpr; BMPR-IA; AU045487; 1110037I22Rik; EC 2.7.11.1; EC 2.7.11.30 |
Gene ID : | 12166 |
mRNA Refseq : | NM_009758 |
Protein Refseq : | NP_033888 |
UniProt ID : | P36895 |
Chromosome Location : | 14 B; 14 13.0 cM |
Pathway : | Cytokine-cytokine receptor interaction; TGF-beta signaling pathway |
Function : | ATP binding; kinase activity; magnesium ion binding; manganese ion binding; metal ion binding; nucleotide binding; protein kinase activity; protein serine/threonine kinase activity; receptor activity; transferase activity; transforming growth factor beta receptor activity; transmembrane receptor protein serine/threonine kinase activity |
Products Types
◆ Recombinant Protein | ||
BMPR1A-361H | Recombinant Human BMPR1A Protein (177-532 aa), His-SUMO-tagged | +Inquiry |
BMPR1A-0788H | Recombinant Human BMPR1A Protein (M1-I532), GST tagged | +Inquiry |
BMPR1A-0787H | Recombinant Human BMPR1A Protein (M1-I532), Tag Free | +Inquiry |
BMPR1A-1043C | Active Recombinant Canine BMPR1A protein(Met1-Arg152), hFc-tagged | +Inquiry |
Bmpr1a-714M | Recombinant Mouse Bmpr1a Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
BMPR1A-2466MCL | Recombinant Mouse BMPR1A cell lysate | +Inquiry |
BMPR1A-2145HCL | Recombinant Human BMPR1A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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