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Recombinant Human EXOSC10, His-tagged

Cat.No. : EXOSC10-26640TH
Product Overview : Recombinant full length EXOSC10 protein produced from Sf9 insect cells. This is a glycosylated, polypeptide chain with a MW of 120 kDa,with a N termial 6xHis tag.
  • Specification
  • Gene Information
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Description : Exosome component 10, also known as EXOSC10, is a human gene, the protein product of which is part of the exosome complex and is an autoantigen is patients with certain auto immune diseases, most notably scleromyositis.
Conjugation : HIS
Biological activity : This protein binds IgG-type human auto-antibodies and polymyositis patient sera.
Form : Liquid
Storage buffer : Preservative: NoneConstituents: 0.02% SDS, 20mM HEPES, 100mM Sodium chloride, 0.01mM EDTA, pH 7.5
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequence Similarities : Contains 1 3-5 exonuclease domain.Contains 1 HRDC domain.
Gene Name : EXOSC10 exosome component 10 [ Homo sapiens ]
Official Symbol : EXOSC10
Synonyms : EXOSC10; exosome component 10; PMSCL2, polymyositis/scleroderma autoantigen 2, 100kDa; p2; p3; p4; PM Scl; PM/Scl 100; polymyositis/scleroderma autoantigen 2 (100kD); RRP6; Rrp6p;
Gene ID : 5394
mRNA Refseq : NM_001001998
Protein Refseq : NP_001001998
MIM : 605960
Uniprot ID : Q01780
Chromosome Location : 1p36.22
Pathway : RNA degradation, organism-specific biosystem; RNA degradation, conserved biosystem;
Function : 3-5 exonuclease activity; RNA binding; exoribonuclease activity; hydrolase activity; nucleotide binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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