Recombinant Human Chemokine (C-C Motif) Ligand 2
Cat.No. : | CCL2-124H |
- Specification
- Gene Information
- Related Products
Cat. No. : | CCL2-124H |
Description : | Monocyte chemotactic protein-1 (MCP-1) is an essential chemokine produced predominantly by macrophages and endothelial cells and is a potent chemotactic factor for monocytes. It can induce the proliferation and activation of killer cells known as CHAK (CC-Chemokine-activated killer). MCP-1 is also a potent activator of human basophils, induces degranulation and the release of histamines. MCP-1 is involved in the pathogenesis of atherosclerosis and myocardial infarction. |
Source : | Mammalian cells |
State Of Matter : | Lyophilized. |
Purity : | >97% by SDS Page and analyzed by silver stain. |
Endotoxin : | <0.1 ng per 1 µg as determined by the LAL method. |
Molecular Weight : | The predicted molecular weight of Recombinant Human MCP-1 is Mr 35 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 70-95 kDa. |
Storage And Stability : | This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |
Gene Name : | CCL2 chemokine (C-C motif) ligand 2 [ Homo sapiens ] |
Synonyms : | CCL2; chemokine (C-C motif) ligand 2; GDCF-2; HC11; HSMCR30; MCAF; MCP-1; MCP1; MGC9434; SCYA2; SMC-CF; monocyte chemoattractant protein-1; monocyte chemotactic and activating factor; monocyte secretory protein JE; small inducible cytokine A2; small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je); small inducible cytokine subfamily A (Cys-Cys), member 2; Monocyte chemoattractant protein 1; Monocyte chemotactic and activating factor; Monocyte chemotactic protein 1; Monocyte secretory protein JE; Small-inducible cytokine A2 |
Gene ID : | 6347 |
mRNA Refseq : | NM_002982 |
Protein Refseq : | NP_002973 |
MIM : | 158105 |
UniProt ID : | P13500 |
Chromosome Location : | 17q11.2-q12 |
Pathway : | Cytokine-cytokine receptor interaction; Chemokine signaling pathway |
Function : | CCR2 chemokine receptor binding; G-protein-coupled receptor binding; chemokine activity; heparin binding; signal transducer activity; protein kinase activity |
Products Types
◆ Recombinant Protein | ||
Ccl2-173C | Active Recombinant Mouse Ccl2 Protein (73 aa) | +Inquiry |
CCL2-11H | Active Recombinant Human CCL2 Protein, His-tagged | +Inquiry |
Ccl2-2030M | Active Recombinant Mouse Ccl2 Protein | +Inquiry |
CCL2-267H | Active Recombinant Human CCL2 Protein (Gln24-Thr99), N-His tagged, Animal-free, Carrier-free | +Inquiry |
CCL2-337C | Active Recombinant Human CCL2 Protein (76 aa) | +Inquiry |
◆ Lysates | ||
CCL2-001MCL | Recombinant Mouse CCL2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket