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Recombinant Human FABP3, His-tagged

Cat.No. : FABP3-26177TH
Product Overview : Recombinant full length human Cardiac FABP with His tag; amino acids 1-133 , 19.1 kDa.
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Description : The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer.
Conjugation : HIS
Source : E. coli
Form : Liquid
Purity : >95% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, pH 8.0
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids : MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMVD AFLGTWKLVD SKNFDDYMKS LGVGFATRQV ASMTKPTTII EKNGDILTLK THSTFKNTEI SFKLGVEFDE TTADDRKVKS IVTLDGGKLV HLQKWDGQET TLVRELIDGK LILTLTHGTA VCTRTYEKEA
Sequence Similarities : Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Gene Name : FABP3 fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) [ Homo sapiens ]
Official Symbol : FABP3
Synonyms : FABP3; fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor); FABP11, fatty acid binding protein 11 , MDGI; fatty acid-binding protein, heart; H FABP; O FABP;
Gene ID : 2170
mRNA Refseq : NM_004102
Protein Refseq : NP_004093
MIM : 134651
Uniprot ID : P05413
Chromosome Location : 1p33-p32
Pathway : PPAR signaling pathway, organism-specific biosystem; PPAR signaling pathway, conserved biosystem;
Function : fatty acid binding; icosatetraenoic acid binding; lipid binding; long-chain fatty acid transporter activity; transporter activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How is FABP3 different from other cardiac biomarkers like troponin? 10/18/2022

While troponin is specific to cardiac muscle and indicative of myocardial damage, FABP3 reflects early-stage cardiac injury and is more sensitive in certain contexts.

Are FABP3 levels specific to heart-related issues? 05/17/2021

While FABP3 is primarily associated with cardiac issues, elevated levels can also be observed in conditions affecting skeletal muscle.

Is FABP3 exclusively a diagnostic marker or does it have prognostic value? 04/25/2020

FABP3 not only helps in diagnosis but also has prognostic value, providing insights into the potential outcomes and recovery of cardiovascular patients.

Can FABP3 be used for early detection of heart attacks? 01/06/2020

Yes, FABP3 is considered a sensitive marker for early detection of myocardial infarction (heart attack).

How does FABP3 contribute to risk assessment in cardiovascular patients? 01/31/2017

Monitoring FABP3 levels helps assess the severity of cardiac damage and aids in risk stratification for cardiovascular events.

Customer Reviews (3)

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Reviews
07/01/2020

    In WB experiments, the FABP3 Protein consistently delivers exceptional performance.

    04/03/2018

      This protein has consistently demonstrated outstanding results, making it an indispensable tool in my research endeavors.

      12/07/2017

        The FABP3 Protein's applicability in protein electron microscopy structure analysis is remarkable.

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