Recombinant Human FASN, His-tagged
Cat.No. : | FASN-28809TH |
Product Overview : | Recombinant fragment, corresponding to amino acids 2181-2502 of Human Fatty Acid Synthase with an N terminal His tag; MWt 37 kDa |
- Specification
- Gene Information
- Related Products
Description : | The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. |
Conjugation : | HIS |
Source : | E. coli |
Tissue specificity : | Ubiquitous. Prominent expression in brain, lung, and liver. |
Form : | Lyophilised:Reconstitute with 64 μl aqua dest. |
Storage buffer : | Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | QLTLRKLQELSSKADEASELACPTP KEDGLAQQQTQLNLR SLLVNPEGPTLMRLNSVQSSERPLF LVHPIEGSTTVFH SLASRLSIPTYGLQCTRAAPLDSIH SLAAYYIDCIRQV QPEGPYRVAGYSYGACVAFEMCSQL QAQQSPAPTHNSL FLFDGSPTYVLAYTQSYRAKLTPGC EAEAETEAICFFVQQFTDMEHNRVL EALLPLKGLEERVAAAVDLIIKSHQ GLD RQELSFAARSFYYKLRAAEQYTPKA KYHGNVMLLRAKT GGAYGEDLGADYNLSQVCDGKVSVH VIEGDHRTLLEGS GLESIISIIHSSLA |
Sequence Similarities : | Contains 1 acyl carrier domain. |
Gene Name : | FASN fatty acid synthase [ Homo sapiens ] |
Official Symbol : | FASN |
Synonyms : | FASN; fatty acid synthase; FAS; SDR27X1; short chain dehydrogenase/reductase family 27X; member 1; |
Gene ID : | 2194 |
mRNA Refseq : | NM_004104 |
Protein Refseq : | NP_004095 |
MIM : | 600212 |
Uniprot ID : | P49327 |
Chromosome Location : | 17q25 |
Pathway : | ChREBP activates metabolic gene expression, organism-specific biosystem; Fatty Acid Biosynthesis, organism-specific biosystem; Fatty Acyl-CoA Biosynthesis, organism-specific biosystem; Fatty acid biosynthesis, organism-specific biosystem; Fatty acid biosynthesis, conserved biosystem; |
Function : | 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity; 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; 3-oxoacyl-[acyl-carrier-protein] synthase activity; [acyl-carrier-protein] S-acetyltransferase activity; [acyl-carrier-protein] S-; |
Products Types
◆ Recombinant Protein | ||
FASN-2924H | Recombinant Human FASN Protein, His (Fc)-Avi-tagged | +Inquiry |
FASN-0482H | Recombinant Human FASN Protein (Q1109-G1524), His tagged | +Inquiry |
FASN-718H | Recombinant Human FASN Protein, His/GST-tagged | +Inquiry |
FASN-3121M | Recombinant Mouse FASN Protein, His (Fc)-Avi-tagged | +Inquiry |
FASN-0481H | Recombinant Human FASN Protein (Q1109-G1524), Tag Free | +Inquiry |
◆ Lysates | ||
FASN-597HCL | Recombinant Human FASN cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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