Recombinant Human Cadherin 1, Type 1, E-Cadherin (Epithelial)
Cat.No. : | CDH1-1605H |
- Specification
- Gene Information
- Related Products
Cat. No. : | CDH1-1605H |
Description : | Cadherin 1, type 1, E-cadherin (epithelial), also known as CDH1 and CD32, is a tumor suppressor gene. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. E-cadherin-mediated cell-cell adhesion pathway may represent a novel chemotherapeutic target for bladder cancer, prostate cancer, and renal-cell carcinoma. |
Source : | Mammalian cells |
Molecular Weight : | The predicted molecular weight of Recombinant Human E-Cadherin is 87.7 kDa. However, the actual molecular weight as observed by migration on SDS Page is 120 kDa. |
State Of Matter : | Lyophilized. |
Purity : | >90% by SDS Page and analyzed by silver stain. |
Endotoxin : | <1.0 EU/µg as determined by the LAL method. |
Storage : | This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. |
Gene Name : | CDH1 cadherin 1, type 1, E-cadherin (epithelial) [ Homo sapiens ] |
Synonyms : | CDH1; cadherin 1, type 1, E-cadherin (epithelial); UVO; CDHE; ECAD; LCAM; Arc-1; CD324; cadherin 1, type 1; uvomorulin; cell-CAM 120/80; cadherin 1, E-cadherin (epithelial); calcium-dependent adhesion protein, epithelial; uvomorulin; Cadherin-1; E-cadherin; CAM 120/80; E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3; Uvomorulin; CD324 antigen; Epithelial cadherin |
Gene ID : | 999 |
mRNA Refseq : | NM_004360 |
Protein Refseq : | NP_004351 |
MIM : | 192090 |
UniProt ID : | P12830 |
Chromosome Location : | 16q22.1 |
Pathway : | Adherens junction; Bladder cancer; Cell adhesion molecules (CAMs); Endometrial cancer; Melanoma; Pathogenic Escherichia coli infection - EHEC; Pathways in cancer; Thyroid cancer; Apoptosis; Cell-cell adhesion systems; Integrin cell surface interactions; Signaling in Immune system |
Function : | RPTP-like protein binding; beta-catenin binding; calcium ion binding; cell adhesion molecule binding; protein phosphatase binding; transcription activator activity |
Products Types
◆ Recombinant Protein | ||
Cdh1-858M | Recombinant Mouse Cdh1 Protein, MYC/DDK-tagged | +Inquiry |
CDH1-41H | Recombinant Human CDH1 Protein, C-8His tagged, Biotinylated | +Inquiry |
CDH1-946R | Recombinant Rat CDH1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CDH1-3118H | Recombinant Human CDH1 Protein, MYC/DDK-tagged | +Inquiry |
CDH1-208H | Recombinant Human CDH1 Protein, Fc-tagged | +Inquiry |
◆ Lysates | ||
CDH1-1892MCL | Recombinant Mouse CDH1 cell lysate | +Inquiry |
CDH1-938HCL | Recombinant Human CDH1 cell lysate | +Inquiry |
CDH1-736RCL | Recombinant Rat CDH1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket