Native Human FN1
Cat.No. : | FN1-28900TH |
Product Overview : | Full length Human Fibronectin , Heterodimer, 550kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined. |
Tissue specificity : | Plasma FN (soluble dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. Ugl-Y1, Ugl-Y2 and Ugl-Y3 are f |
Form : | Lyophilised:Reconstitute with 1.0 milliliters of water to achieve 2.0 mg/mL. |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 20mM HEPES, 150mM Sodium chloride, pH 7.4 |
Storage : | Store at 4°C. Upon reconstitution store at -80oC. |
Sequence Similarities : | Contains 12 fibronectin type-I domains.Contains 2 fibronectin type-II domains.Contains 16 fibronectin type-III domains. |
Gene Name : | FN1 fibronectin 1 [ Homo sapiens ] |
Official Symbol : | FN1 |
Synonyms : | FN1; fibronectin 1; fibronectin; CIG; cold insoluble globulin; FINC; GFND2; LETS; migration stimulating factor; MSF; |
Gene ID : | 2335 |
mRNA Refseq : | NM_002026 |
Protein Refseq : | NP_002017 |
MIM : | 135600 |
Uniprot ID : | P02751 |
Chromosome Location : | 2q34 |
Pathway : | Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Angiopoietin receptor Tie2-mediated signaling, organism-specific biosystem; Bacterial invasion of epithelial cells, organism-specific biosystem; Bacterial invasion of epithelial cells, conserved biosystem; |
Function : | collagen binding; extracellular matrix structural constituent; heparin binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
FN1-3296M | Recombinant Mouse FN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
FN1-938H | Recombinant Human FN1 Protein, His-tagged | +Inquiry |
FN1-4400H | Recombinant Human FN1 Protein, GST-tagged | +Inquiry |
FN1-2959H | Recombinant Human FN1 Protein, His (Fc)-Avi-tagged | +Inquiry |
FN1-2741P | Recombinant Pig FN1 Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
FN1-2708H | Native Human FN1 protein | +Inquiry |
FN1-700H | Native Human Fibronectin 1 | +Inquiry |
FN1-3B | Active Bovine Fibronectin, carrier free | +Inquiry |
◆ Lysates | ||
FN1-2956HCL | Recombinant Human FN1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionIt is expressed in a variety of organs and tissues, including skin, kidneys, cardiovascular system, liver, etc.
FN1 protein is involved in the migration, adhesion and activation of inflammatory cells during the inflammatory response, and plays an important role in the development of inflammation.
Yes, multiple factors have been found to regulate the expression and function of FN1 protein, including transcription factors, growth factors, etc.
FN1 protein is involved in the invasion and metastasis of tumor cells, which can provide matrix support and guide signals to promote the migration and invasion of tumor cells.
This protein is involved in key steps such as fibrosis, angiogenesis and interstitial cell proliferation in the wound healing process, and plays an important role in wound repair.
The protein plays an important role in key steps such as extracellular matrix remodeling, cell adhesion, and directed differentiation of mesenchymal stem cells during tissue repair.
Customer Reviews (3)
Write a reviewThe preservation conditions are wide and the efficiency is high.
Experimental process is convenient, which greatly improves the efficiency of scientific research.
Biological activity of this protein is amazing, and you can see that its production process is very pure, which has a crucial effect on the quality of the product.
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