Recombinant Human FUS, His-tagged
Cat.No. : | FUS-30143TH |
Product Overview : | Recombinant fragment, corresponding to amino acids 262-526 of Human TLS/FUS with an N-terminal His tag; Predicted MWt 29 kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. |
Conjugation : | HIS |
Source : | E. coli |
Tissue specificity : | Ubiquitous. |
Form : | Lyophilised:Reconstitute with 106 μl aqua dest. |
Storage buffer : | Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | FNKFGGPRDQGSRHDSEQDNSDNNT IFVQGLGENVTIESV ADYFKQIGIIKTNKKTGQPMINLYT DRETGKLKGEATV SFDDPPSAKAAIDWFDGKEFSGNPI KVSFATRRADFNR GGGNGRGGRGRGGPMGRGGYGGGGS GGGGRGGFPSGGG GGGGQQRAGDWKCPNPTCENMNFSW RNECNQCKAPKPDGPGGGPGGSHMG GNYGDDRRGGRGGYDRGGYRGRGGD RGG FRGGRGGGDRGGFGPGKMDSRGEHR QDRRERPY |
Sequence Similarities : | Belongs to the RRM TET family.Contains 1 RanBP2-type zinc finger.Contains 1 RRM (RNA recognition motif) domain. |
Gene Name : | FUS fused in sarcoma [ Homo sapiens ] |
Official Symbol : | FUS |
Synonyms : | FUS; fused in sarcoma; ALS6, amyotrophic lateral sclerosis 6 , fusion (involved in t(12;16) in malignant liposarcoma) , fusion, derived from t(12;16) malignant liposarcoma; RNA-binding protein FUS; FUS1; heterogeneous nuclear ribonucleoprotein P2; hnRN |
Gene ID : | 2521 |
mRNA Refseq : | NM_001170634 |
Protein Refseq : | NP_001164105 |
MIM : | 137070 |
Uniprot ID : | P35637 |
Chromosome Location : | 16p11.2 |
Pathway : | Formation and Maturation of mRNA Transcript, organism-specific biosystem; Gene Expression, organism-specific biosystem; Processing of Capped Intron-Containing Pre-mRNA, organism-specific biosystem; Transcriptional misregulation in cancers, organism-specific biosystem; Transcriptional misregulation in cancers, conserved biosystem; |
Function : | DNA binding; RNA binding; metal ion binding; nucleotide binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
FUS-4555H | Recombinant Human FUS Protein, GST-tagged | +Inquiry |
FUS-06H | Active Recombinant Human FUS Protein, Myc/DDK-tagged | +Inquiry |
FUS-461H | Recombinant Human FUS Protein, His-tagged | +Inquiry |
Fus-3107M | Recombinant Mouse Fus Protein, Myc/DDK-tagged | +Inquiry |
FUS-3391M | Recombinant Mouse FUS Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
FUS-6118HCL | Recombinant Human FUS 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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