Recombinant Human GALK1, His-tagged

• Cat.No.: GALK1-28118TH
• Product Overview: Recombinant full length Human GALK1 with a N terminal His tag. 412 amino acids with a predicted MWt 44.4 kDa including tag.

Specification

• Description: Galactokinase is a major enzyme for the metabolism of galactose and its deficiency causes congenital cataracts during infancy and presenile cataracts in the adult population.
• Protein length: 392 amino acids
• Conjugation: HIS
• Molecular Weight: 44.400kDa inclusive of tags
• Source: E. coli
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: pH: 8.00Constituents:0.32% Tris HCl, 10% Glycerol
• Storage: Please see Notes section
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MAALRQPQVA ELLAEARRAF REEFGAEPEL AVSAPGRVNL IGEHTDYNQG LVLPMALELM TVLVGSPRKD GLVSLLTTSE GADEPQRLQF PLPTAQRSLE PGTPRWANYV KGVIQYYPAA PLPGFSAVVV SSVPLGGGLS SSASLEVATY TFLQQLCPDS GTIAARAQVC QQAEHSFAGM PCGIMDQFIS LMGQKGHALL IDCRSLETSL VPLSDPKLAV LITNSNVRHS LASSEYPVRR RQCEEVARAL GKESLREVQL EELEAARDLV SKEGFRRARH VVGEIRRTAQ AAAALRRGDY RAFGRLMVES HRSLRDDYEV SCPELDQLVE AALAVPGVYG SRMTGGGFGG CTVTLLEASA APHAMRHIQE HYGGTATFYL SQAADGAKVL CL
• Sequence Similarities: Belongs to the GHMP kinase family. GalK subfamily.

Gene Information

• Gene Name: GALK1 galactokinase 1 [ Homo sapiens ]
• Official Symbol: GALK1
• Synonyms: GALK1; galactokinase 1; GALK; galactokinase
• Gene ID: 2584
• mRNA Refseq: NM_000154
• Protein Refseq: NP_000145
• MIM: 604313
• Uniprot ID: P51570
• Chromosome Location: 17q23-q25
• Pathway: Amino sugar and nucleotide sugar metabolism, organism-specific biosystem; Amino sugar and nucleotide sugar metabolism, conserved biosystem; Galactose catabolism, organism-specific biosystem; Galactose metabolism, organism-specific biosystem; Galactose metabolism, conserved biosystem
• Function: ATP binding; galactokinase activity; galactose binding; kinase activity; nucleotide binding