Native Human GC

• Cat.No.: GC-29857TH
• Product Overview: Full length Human Vitamin D Binding Protein purified from Human Plasma; amino acids 17-474, MWt 50-52kDa.

Specification

• Description: The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Form: Lyophilised:Reconstitute with deionized water to pre-lyophilised volume.
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 0.15M Sodium chloride, 20mM Dibasic monohydrogen sodium phosphate, pH 7.4
• Storage: Shipped at 4°C. Store at -20oC.
• Sequence Similarities: Belongs to the ALB/AFP/VDB family.Contains 3 albumin domains.

Gene Information

• Gene Name: GC group-specific component (vitamin D binding protein) [ Homo sapiens ]
• Official Symbol: GC
• Synonyms: GC; group-specific component (vitamin D binding protein); vitamin D-binding protein; DBP; hDBP; VDBP
• Gene ID: 2638
• mRNA Refseq: NM_000583
• Protein Refseq: NP_000574
• Uniprot ID: P02774
• Chromosome Location: 4q12-q13
• Pathway: Metabolism of lipids and lipoproteins, organism-specific biosystem; Metabolism of steroid hormones and vitamins A and D, organism-specific biosystem; Vitamin D (calciferol) metabolism, organism-specific biosystem
• Function: actin binding; vitamin D binding; vitamin transporter activity