Recombinant Human GDF10 protein

• Cat.No.: GDF10-27683TH
• Product Overview: Recombinant Human GDF10(369-478aa) was expressed in E. coli.

Specification

• Description: GDF10 (Growth differentiation factor 10) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It is expressed in femur, brain, lung, skeletal, muscle, pancreas and testis, and it plays a role in head formation and may have multiple roles in skeletal morphogenesis. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues.
• Source: E. coli
• Species: Human
• Form: Liquid. In 10 mM sodium citrate (pH 3.5) containing 10% glycerol.
• Molecular Mass: 12.5 kDa (111aa), confirmed by MALDI-TOF.
• AA Sequence: MQWDEPRVCS RRYLKVDFAD IGWNEWIISP KSFDAYYCAG ACEFPMPKIV RPSNHATIQS IVRAVGIIPG IPEPCCVPDK MNSLGVLFLDENRNVVLKVY PNMSVDTCAC R
• Purity: > 95% by SDS - PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: GDF10 growth differentiation factor 10 [ Homo sapiens ]
• Official Symbol: GDF10
• Synonyms: GDF10; growth differentiation factor 10; bone morphogenetic protein 3B; BMP 3b; BIP; GDF-10; bone-inducing protein; BMP3B; BMP-3b
• Gene ID: 2662
• mRNA Refseq: NM_004962
• Protein Refseq: NP_004953
• MIM: 601361
• UniProt ID: P55107
• Chromosome Location: 10q11.22
• Pathway: Adipogenesis, organism-specific biosystem
• Function: cytokine activity; growth factor activity