Recombinant Human GLO1

• Cat.No.: GLO1-29068TH
• Product Overview: Recombinant full length Human GLO1; amino acids 1-184 , 20.7kDa.

Specification

• Description: The enzyme encoded by this gene is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione.Glyoxalase I is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere.
• Source: E. coli
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MAEPQPPSGG LTDEAALSCC SDADPSTKDF LLQQTMLRVK DPKKSLDFYT RVLGMTLIQK CDFPIMKFSL YFLAYEDKND IPKEKDEKIA WALSRKATLE LTHNWGTEDD ETQSYHNGNS DPRGFGHIGI AVPDVYSACK RFEELGVKFV KKPDDGKMKG LAFIQDPDGY WIEILNPNKM ATLM
• Sequence Similarities: Belongs to the glyoxalase I family.

Gene Information

• Gene Name: GLO1 glyoxalase I [ Homo sapiens ]
• Official Symbol: GLO1
• Synonyms: GLO1; glyoxalase I; lactoylglutathione lyase; GLOD1; glyoxalase domain containing 1
• Gene ID: 2739
• mRNA Refseq: NM_006708
• Protein Refseq: NP_006699
• MIM: 138750
• Uniprot ID: Q04760
• Chromosome Location: 6p21.3-p21.1
• Pathway: Pyruvate metabolism, organism-specific biosystem; Pyruvate metabolism, conserved biosystem
• Function: lactoylglutathione lyase activity; lyase activity; metal ion binding