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Recombinant Human GM2A

Cat.No. : GM2A-27456TH
Product Overview : Recombinant fragment of Human GM2A with N terminal proprietary tag; Predicted MW 36.63 kDa
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.
Protein length : 100 amino acids
Molecular Weight : 36.630kDa inclusive of tags
Source : Wheat germ
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : WIKIPCTDYIGSCTFEHFCDVLDML IPTGEPCPEPLRTYGLPCHCPFKEG TYSLPKSEFVVPDLELPSWLTTGNY RIESVLSSSGKRLGCIKIAASLKGI
Gene Name : GM2A GM2 ganglioside activator [ Homo sapiens ]
Official Symbol : GM2A
Synonyms : GM2A; GM2 ganglioside activator; GM2 ganglioside activator protein; ganglioside GM2 activator; cerebroside sulfate activator protein; SAP 3; sphingolipid activator protein 3;
Gene ID : 2760
mRNA Refseq : NM_000405
Protein Refseq : NP_000396
MIM : 613109
Uniprot ID : P17900
Chromosome Location : 5q33.1
Pathway : Lysosome, organism-specific biosystem; Lysosome, conserved biosystem;
Function : beta-N-acetylhexosaminidase activity; sphingolipid activator protein activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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