Recombinant Human Ephrin-A3

• Cat.No.: EFNA3-1609H

Specification

• Cat. No.: EFNA3-1609H
• Description: Ephrin-A3, also known as EFNA3 encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Ephrin-A3 encodes an EFNA class ephrin.
• Source: Mammalian cells
• Molecular Weight: The predicted molecular weight of Recombinant Human Ephrin-A3 is 47.7 kDa. However, the actual molecular weight as observed by migration on SDS Page is 90 kDa.
• State Of Matter: Lyophilized.
• Formulation: This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives.
• Purity: >90% by SDS Page and analyzed by silver stain.
• Endotoxin: <1.0 EU/µg as determined by the LAL method.
• Storage: This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Gene Information

• Gene Name: EFNA3 ephrin-A3 [ Homo sapiens ]
• Synonyms: EFNA3; ephrin-A3; EFL2; EPLG3; LERK3; Ehk1-L; ephrin A3; ligand of eph-related kinase 3; eph-related receptor tyrosine kinase ligand 3; EPH-related receptor tyrosine kinase ligand 3; LERK-3; EHK1-L; EFL-2; OTTHUMP00000033243; EHK1 ligand
• Gene ID: 1944
• mRNA Refseq: NM_004952
• Protein Refseq: NP_004943
• MIM: 601381
• UniProt ID: P52797
• Chromosome Location: 1q21-q22
• Pathway: Axon guidance
• Function: transmembrane-ephrin receptor activity