Recombinant Human GNAO1, His-tagged

• Cat.No.: GNAO1-28088TH
• Product Overview: Recombinant fragment, corresponding to amino acids 8-329 of Human G0 Protein alpha with N terminal His tag, 322 amino acids, 37kDa.

Specification

• Conjugation: HIS
• Source: E. coli
• Form: Lyophilised:Reconstitute with 133 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: EERAALERSKAIEKNLKEDGISAAK DVKLLLLGAGESGKS TIVKQMKIIHEDGFSGEDVKQYKPV VYSNTIQSLAAIV RAMDTLGIEYGDKERKADAKMVCDV VSRMEDTEPFSAE LLSAMMRLWGDSGIQECFNRSREYQ LNDSAKYYLDSLD RIGAADYQPTEQDILRTRVKTTGIV ETHFTFKNLHFRL FDVGGQRSERKKWIHCFEDVTAIIF CVALSGYDQVLHE DETTNRMHESLMLFDSICNNKFFID TSIILFLNKKDLFGEKIKKSPLTIC FPEYTGPNTYEDAAAYIQAQFESKN RSP NKEIYCHMTCATDT
• Sequence Similarities: Belongs to the G-alpha family. G(i/o/t/z) subfamily.

Gene Information

• Gene Name: GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O [ Homo sapiens ]
• Official Symbol: GNAO1
• Synonyms: GNAO1; guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O; guanine nucleotide-binding protein G(o) subunit alpha; G ALPHA o
• Gene ID: 2775
• mRNA Refseq: NM_020988
• Protein Refseq: NP_066268
• MIM: 139311
• Uniprot ID: P09471
• Chromosome Location: 16q13
• Pathway: Calcium Regulation in the Cardiac Cell, organism-specific biosystem; Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem; Cholinergic synapse, organism-specific biosystem; Dopaminergic synapse, organism-specific biosystem
• Function: G-protein beta/gamma-subunit complex binding; GTP binding; GTPase activity; guanyl nucleotide binding; metabotropic serotonin receptor binding