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Recombinant Human GNB2L1, His-tagged

Cat.No. : GNB2L1-30327TH
Product Overview : Recombinant full length Human RACK1 protein with an N terminal His tag. Observed MWt: 37kDa.
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  • Gene Information
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Description : Seems to bind protein kinase C acting as an intracellular receptor to anchor the activated PKC to the cytoskeleton. May be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1.
Conjugation : HIS
Source : E. coli
Form : Lyophilised:Reconstitute with 87 μl aqua dest.
Storage buffer : Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
Storage : Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : MTEQMTLRGTLKGHNGWVTQIATTP QFPDMILSASRDKTI IMWKLTRDETNYGIPQRALRGHSHF VSDVVISSDGQFA LSGSWDGTLRLWDLTTGTTTRRFVG HTKDVLSVAFSSDNRQIVSGSRDKT IKLWNTLGVCKYTVQDESHSEWVSC VRF SPNSSNPIIVSCGWDKLVKVWNLAN CKLKTNHIGHTGY LNTVTVSPDGSLCASGGKDGQAMLW DLNEGKHLYTLDGGD IINALCFSPNRYWLCAATGPSIKIW DLEGKIIVDELKQ EVISTSSKAEPPQCTSLAWSADGQT LFAGYTDNLVRVW QVTIGTR
Sequence Similarities : Belongs to the WD repeat G protein beta family.Contains 7 WD repeats.
Gene Name : GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 [ Homo sapiens ]
Official Symbol : GNB2L1
Synonyms : GNB2L1; guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1; guanine nucleotide-binding protein subunit beta-2-like 1; Gnb2 rs1; H12.3; RACK1; Receptor for Activated C Kinase 1;
Gene ID : 10399
mRNA Refseq : NM_006098
Protein Refseq : NP_006089
MIM : 176981
Uniprot ID : P63244
Chromosome Location : 5q35.3
Pathway : CXCR4-mediated signaling events, organism-specific biosystem; Hypoxic and oxygen homeostasis regulation of HIF-1-alpha, organism-specific biosystem; IGF1 pathway, organism-specific biosystem; IL-2 Signaling Pathway, organism-specific biosystem; IL-3 Signaling Pathway, organism-specific biosystem;
Function : SH2 domain binding; ion channel inhibitor activity; protein binding; protein kinase C binding; protein phosphatase binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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