Recombinant Mouse Eph Receptor A4

• Cat.No.: Epha4-1724M

Specification

• Cat. No.: Epha4-1724M
• Description: EPH receptor A4 (ephrin type-A receptor 4) is a protein that in humans is encoded by the EPHA4 gene. This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
• Molecular Weight: The predicted molecular weight of Recombinant Mouse EphA4 is Mr 85.7 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 110 kDa.
• Source: Mammalian cells
• State Of Matter: Lyophilized.
• Purity: >95% by SDS Page and analyzed by silver stain.
• Endotoxin: <0.1 ng per 1 µg as determined by the LAL method.
• Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Gene Information

• Gene Name: Epha4 Eph receptor A4 [ Mus musculus ]
• Synonyms: Epha4; Eph receptor A4; rb; Sek; Cek8; Hek8; Sek1; Tyro1; AI385584; 2900005C20Rik; ephrin receptor EphA4; rabbit; snoRNA MBII-267; EC 2.7.10.1
• Gene ID: 13838
• mRNA Refseq: NM_007936
• Protein Refseq: NP_031962
• UniProt ID: Q03137
• Chromosome Location: 1 C1-C5; 1 43.0 cM
• Pathway: Axon guidance
• Function: ATP binding; ephrin receptor activity; kinase activity; nucleotide binding; protein binding; protein kinase activity; protein tyrosine kinase activity; receptor activity; transferase activity; transmembrane receptor protein tyrosine kinase activity