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Native Human HPX

Cat.No. : HPX-29307TH
Product Overview : Full length native Human Hemopexin purified from pooled normal Human serum/plasma, aa 24-462, 51kDa.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a plasma glycoprotein that binds heme with high affinity. The encoded protein is an acute phase protein that transports heme from the plasma to the liver and may be involved in protecting cells from oxidative stress.
Source : Human Plasma
Species : Human
Form : Lyophilised:Use of phosphate buffer, pH >7.0 containing 0.15M NaCl is recommended.
Molecular Mass : 51kDa
Protein length : 439 amino acids
Purity : by SDS-PAGE
Storage : Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
Storage Buffer : Preservative: NoneConstituents: 0.02M Ammonium bicarbonate
Gene Name : HPX hemopexin [ Homo sapiens ]
Official Symbol : HPX
Synonyms : HPX; hemopexin; beta-1B-glycoprotein; HX; FLJ56652;
Gene ID : 3263
mRNA Refseq : NM_000613
Protein Refseq : NP_000604
MIM : 142290
UniProt ID : P02790
Chromosome Location : 11p15.5-p15.4
Function : binding; heme transporter activity; metal ion binding; protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can HPX be used as a diagnostic marker for hemolytic disorders? 03/08/2022

Yes, low levels of HPX in the blood can be an indicator of hemolytic disorders.

How is HPX involved in managing heme in the body? 10/27/2021

HPX binds to free heme released from hemoglobin, preventing its toxic effects and aiding in its clearance.

How does HPX contribute to the prevention of heme-related toxicity? 04/07/2021

HPX binds to heme, preventing its oxidative and inflammatory damage to tissues and organs.

What clinical conditions are associated with heme release, making HPX relevant? 06/10/2018

Hemolysis, hemoglobinopathies, and various types of anemias can lead to heme release, highlighting the clinical relevance of HPX.

How is HPX regulated in the body, and can its levels be influenced by medications? 12/16/2017

HPX levels can be influenced by various factors, including inflammation and medications like glucocorticoids.

Customer Reviews (3)

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Reviews
12/09/2019

    the manufacturer offers a wide range of HPX protein variants, including recombinant or native forms, as well as different conjugates and modifications.

    02/02/2018

      As a researcher using HPX protein, I have found numerous advantages in its application during trials for various experimental purposes.

      08/15/2017

        the HPX protein is known for its strong affinity for phospholipids, particularly phosphatidylserine (PS), on the outer leaflet of cell membranes.

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