Recombinant Human HRH2

• Cat.No.: HRH2-27612TH
• Product Overview: Recombinant full length Human Histamine H2 Receptor with N terminal FLAG tag fused at the C terminal to the N terminal of Human Gq alpha via a His tag,90 kDa expressed in Sf9 insect cells.

Specification

• Description: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Conjugation: FLAG,His
• Form: Liquid
• Storage buffer: Preservative: NoneConstituents: 75mM Tris HCl, 12.5mM Magnesium chloride, 1mM EDTA, pH 7.4
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.

Gene Information

• Gene Name: HRH2 histamine receptor H2 [ Homo sapiens ]
• Official Symbol: HRH2
• Synonyms: HRH2; histamine receptor H2; histamine H2 receptor
• Gene ID: 3274
• mRNA Refseq: NM_001131055
• Protein Refseq: NP_001124527
• MIM: 142703
• Uniprot ID: P25021
• Chromosome Location: 5q35
• Pathway: Amine ligand-binding receptors, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem
• Function: G-protein coupled receptor activity; histamine receptor activity; receptor activity; signal transducer activity