Recombinant Human HSF1, His-tagged

• Cat.No.: HSF1-29387TH
• Product Overview: Recombinant full length Human HSF1 with N-terminal His-tag. 549 aa; Mol Wt 59 kDa inclusive of tag.

Specification

• Description: The product of this gene is a heat-shock transcription factor. Transcription of heat-shock genes is rapidly induced after temperature stress. Hsp90, by itself and/or associated with multichaperone complexes, is a major repressor of this gene.
• Protein length: 529 amino acids
• Conjugation: HIS
• Molecular Weight: 59.000kDa inclusive of tags
• Source: E. coli
• Form: Liquid
• Purity: by SDS-PAGE
• Storage buffer: pH: 8.00Constituents:0.24% Tris, 0.29% Sodium chloride, 0.02% DTT
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MDLPVGPGAA GPSNVPAFLT KLWTLVSDPD TDALICWSPS GNSFHVFDQG QFAKEVLPKY FKHNNMASFV RQLNMYGFRK VVHIEQGGLV KPERDDTEFQ HPCFLRGQEQ LLENIKRKVT SVSTLKSEDI KIRQDSVTKL LTDVQLMKGK QECMDSKLLA MKHENEALWR EVASLRQKHA QQQKVVNKLI QFLISLVQSN RILGVKRKIP LMLNDSGSAH SMPKYSRQFS LEHVHGSGPY SAPSPAYSSS SLYAPDAVAS SGPIISDITE LAPASPMASP GGSIDERPLS SSPLVRVKEE PPSPPQSPRV EEASPGRPSS VDTLLSPTAL IDSILRESEP APASVTALTD ARGHTDTEGR PPSPPPTSTP EKCLSVACLD KNELSDHLDA MDSNLDNLQT MLSSHGFSVD TSALLDLFSP SVTVPDMSLP DLDSSLASIQ ELLSPQEPPR PPEAENSSPD SGKQLVHYTA QPLFLLDPGS VDTGSNDLPV LFELGEGSYF SEGDGFAEDP TISLLTGSEP PKAKDPTVS
• Sequence Similarities: Belongs to the HSF family.

Gene Information

• Gene Name: HSF1 heat shock transcription factor 1 [ Homo sapiens ]
• Official Symbol: HSF1
• Synonyms: HSF1; heat shock transcription factor 1; heat shock factor protein 1; HSTF1
• Gene ID: 3297
• mRNA Refseq: NM_005526
• Protein Refseq: NP_005517
• MIM: 140580
• Uniprot ID: Q00613
• Chromosome Location: 8q24.3
• Pathway: Legionellosis, organism-specific biosystem; Legionellosis, conserved biosystem
• Function: protein binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity