Recombinant Human HSPD1

• Cat.No.: HSPD1-28422TH
• Product Overview: Recombinant full length Human Hsp60, 573 amino acids, MWt: 61kDa

Specification

• Description: This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.
• Protein length: 573 amino acids
• Molecular Weight: 61.000kDa
• Source: E. coli
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative:0.09% Sodium azideConstituents:99% PBS, Phosphate Buffer
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequence Similarities: Belongs to the chaperonin (HSP60) family.

Gene Information

• Gene Name: HSPD1 heat shock 60kDa protein 1 (chaperonin) [ Homo sapiens ]
• Official Symbol: HSPD1
• Synonyms: HSPD1; heat shock 60kDa protein 1 (chaperonin); heat shock 60kD protein 1 (chaperonin) , spastic paraplegia 13 (autosomal dominant) , SPG13; 60 kDa heat shock protein, mitochondrial; GROEL; HSP60
• Gene ID: 3329
• mRNA Refseq: NM_002156
• Protein Refseq: NP_002147
• MIM: 118190
• Uniprot ID: P10809
• Chromosome Location: 2q33.1
• Pathway: Legionellosis, organism-specific biosystem; Legionellosis, conserved biosystem; RNA degradation, organism-specific biosystem; RNA degradation, conserved biosystem; SIDS Susceptibility Pathways, organism-specific biosystem
• Function: ATP binding; ATPase activity; DNA replication origin binding; cell surface binding; chaperone binding