Recombinant Human IGFBP3
Cat.No. : | IGFBP3-28257TH |
Product Overview : | Recombinant human IGFBP3 protein (amino acids 28-291); a28.8 kDa protein consisting of 264 amino acid residues. |
- Specification
- Gene Information
- Related Products
Description : | This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
Source : | E. coli |
Tissue specificity : | Expressed by most tissues. Present in plasma. |
Form : | Lyophilised:Reconstitute with water to a concentration of 0.1-1.0mg/ml. |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 20mM Sodium citrate, pH 4Endotoxin level is less than 0.1 ng per μg (1EU/μg). |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Sequences of amino acids : | GASSGGLGPV VRCEPCDARA LAQCAPPPAV CAELVREPGC GCCLTCALSE GQPCGIYTER CGSGLRCQPS PDEARPLQAL LDGRGLCVNA SAVSRLRAYL LPAPPAPGNA SESEEDRSAG EVESPSVSST HRVSDPKFHP LHSKIIIIKK GHAKDSQRYK VDYESQSTDT QNFSSESKRE TEYGPCRREM EDTLNHLKFL NVLSPRGVHI PNCDKKGFYK KKQCRPSKGR KRGFCWCVDK YGQPLPGYTT KGKEDVHCYS MQSK |
Sequence Similarities : | Contains 1 IGFBP N-terminal domain.Contains 1 thyroglobulin type-1 domain. |
Gene Name : | IGFBP3 insulin-like growth factor binding protein 3 [ Homo sapiens ] |
Official Symbol : | IGFBP3 |
Synonyms : | IGFBP3; insulin-like growth factor binding protein 3; insulin-like growth factor-binding protein 3; acid stable subunit of the 140 K IGF complex; binding protein 29; binding protein 53; BP 53; growth hormone dependent binding protein; IBP3; IGF binding pr |
Gene ID : | 3486 |
mRNA Refseq : | NM_000598 |
Protein Refseq : | NP_000589 |
MIM : | 146732 |
Uniprot ID : | P17936 |
Chromosome Location : | 7p13-p12 |
Pathway : | Diabetes pathways, organism-specific biosystem; Direct p53 effectors, organism-specific biosystem; Myometrial Relaxation and Contraction Pathways, organism-specific biosystem; Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs), organism-specific biosystem; Transcriptional misregulation in cancers, organism-specific biosystem; |
Function : | insulin-like growth factor I binding; insulin-like growth factor binding; metal ion binding; protein binding; protein tyrosine phosphatase activator activity; |
Products Types
◆ Recombinant Protein | ||
IGFBP3-12H | Recombinant Human IGFBP3 Protein (28-291aa), N-His-tagged | +Inquiry |
IGFBP3-2678H | Recombinant Human IGFBP3 protein(121-200 aa), C-His-tagged | +Inquiry |
Igfbp3-10570M | Recombinant Mouse Igfbp3 Protein, His (Fc)-Avi-tagged | +Inquiry |
IGFBP3-2039R | Recombinant Rhesus Macaque IGFBP3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Igfbp3-1655M | Recombinant Mouse Igfbp3 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
IGFBP3-1230CCL | Recombinant Cynomolgus IGFBP3 cell lysate | +Inquiry |
IGFBP3-2927HCL | Recombinant Human IGFBP3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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