Recombinant Human IL13
Cat.No. : | IL13-29107TH |
Product Overview : | Recombinant Human IL13 variant 114 amino acid protein with a substitution of Q for R at a single point. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. |
Source : | E. coli |
Biological activity : | A |
Form : | Lyophilised:Centrifuge the vial prior to opening.Reconstitute in 20 mM Acetic Acid to a concentration of 0.1-0.5 mg/ml.Note:Allow the reconstituted vial to sit at 4°C for at >2 hours before use.This solution can then be diluted into other aqueous buffers |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneEndotoxin level is less than 0.1 ng per μg (1EU/μg). |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MSPGPVPPST ALRELIEELV NITQNQKAPL CNGSMVWSIN LTAGMYCAAL ESLINVSGCS AIEKTQRMLS GFCPHKVSAG QFSSLHVRDT KIEVAQFVKD LLLHLKKLFR EGQFN |
Sequence Similarities : | Belongs to the IL-4/IL-13 family. |
Gene Name : | IL13 interleukin 13 [ Homo sapiens ] |
Official Symbol : | IL13 |
Synonyms : | IL13; interleukin 13; interleukin-13; allergic rhinitis; ALRH; BHR1; Bronchial hyperresponsiveness 1 (bronchial asthma); IL 13; MGC116786; MGC116788; MGC116789; P600; |
Gene ID : | 3596 |
mRNA Refseq : | NM_002188 |
Protein Refseq : | NP_002179 |
MIM : | 147683 |
Uniprot ID : | P35225 |
Chromosome Location : | 5q31 |
Pathway : | Asthma, organism-specific biosystem; Asthma, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Cytokines and Inflammatory Response, organism-specific biosystem; |
Function : | cytokine activity; interleukin-13 receptor binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
IL13-4328Z | Recombinant Zebrafish IL13 Protein | +Inquiry |
Il13-038I | Active Recombinant Mouse Il13 Protein (111 aa) | +Inquiry |
Il13-008I | Active Recombinant Rat Il13 Protein (110 aa) | +Inquiry |
Il13-144M | Recombinant Active Mouse IL13 Protein, His-tagged(C-ter) | +Inquiry |
Il13-087M | Active Recombinant Mouse Il13 Protein | +Inquiry |
◆ Lysates | ||
IL13-001HCL | Recombinant Human IL13 cell lysate | +Inquiry |
IL13-1336MCL | Recombinant Mouse IL13 cell lysate | +Inquiry |
IL13-1894CCL | Recombinant Cynomolgus IL13 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (10)
Ask a questionFlow cytometry quantifies IL13 receptor expression on cells.
Transgenic models illuminate IL13's in vivo functions.
ELISA quantifies IL13 secretion in cell cultures accurately.
siRNA knockdown uncovers IL13's specific cellular effects.
Co-immunoprecipitation identifies IL13 signaling partners.
Differential techniques distinguish IL13 and IL4 signaling pathways.
Reporter gene assays gauge IL13-driven transcription.
Microarray analysis profiles IL13-induced gene expression.
Experimental methods reveal IL13's impact on tissue remodeling.
Site-directed mutagenesis identifies key residues in IL13 receptor binding.
Customer Reviews (3)
Write a reviewEffective in Th2 cell differentiation.
Good for cytokine assays.
High yield in expression.
Ask a Question for All IL13 Products
Required fields are marked with *
My Review for All IL13 Products
Required fields are marked with *
Inquiry Basket