Recombinant Human IL17A, Fc-tagged
Cat.No. : | IL17A-28212TH |
Product Overview : | Recombinant full length Human IL17 fused at the C-terminus to the Fc portion of Human IgG1; MWt 45 kDa . |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. |
Protein length : | 155 amino acids |
Conjugation : | Fc |
Molecular Weight : | 45.000kDa inclusive of tags |
Source : | HEK 293 cells |
Tissue specificity : | Restricted to activated memory T-cells. |
Form : | Liquid |
Purity : | >90% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: PBS |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the IL-17 family. |
Gene Name : | IL17A interleukin 17A [ Homo sapiens ] |
Official Symbol : | IL17A |
Synonyms : | IL17A; interleukin 17A; CTLA8, IL17, interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8); interleukin-17A; cytotoxic T lymphocyte associated protein 8; IL 17; IL 17A; |
Gene ID : | 3605 |
mRNA Refseq : | NM_002190 |
Protein Refseq : | NP_002181 |
MIM : | 603149 |
Uniprot ID : | Q16552 |
Chromosome Location : | 6p12 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; IL23-mediated signaling events, organism-specific biosystem; IL27-mediated signaling events, organism-specific biosystem; Rheumatoid arthritis, organism-specific biosystem; |
Function : | cytokine activity; |
Products Types
◆ Recombinant Protein | ||
IL17A-148H | Recombinant Active Human IL17A Protein, His-tagged(C-ter) | +Inquiry |
IL17A-15P | Recombinant Pig IL17A Protein (Gly26-Ser155), C-His tagged, Animal-free, Carrier-free | +Inquiry |
IL17A-139M | Active Recombinant Mouse IL17A Protein | +Inquiry |
IL17A-381M | Active Recombinant Mouse IL17A Protein, His-tagged | +Inquiry |
IL17A-441R | Active Recombinant Rabbit IL17 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
IL17A-001HCL | Recombinant Human IL17A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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