Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human JUN

Cat.No. : JUN-27752TH
Product Overview : Recombinant fragment: MTAKMETTFY DDALNASFLP SESGPYGYSN PKILKQSMTL NLADPVGSLK PHLRAKNSDL LTSPDVGLLK LASPELERL, corresponding to N terminal amino acids 1-79 of Human c-Jun with N-terminal proprietary tag.
  • Specification
  • Gene Information
  • Related Products
Description : This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.
Source : E. coli
Form : Liquid
Storage buffer : Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM PMSF, pH 7.5
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : MTAKMETTFYDDALNASFLPSESGP YGYSNPKILKQSMTLNLADPVGSLK PHLRAKNSDLLTSPDVGLLKLASPE LERL
Sequence Similarities : Belongs to the bZIP family. Jun subfamily.Contains 1 bZIP domain.
Gene Name : JUN jun proto-oncogene [ Homo sapiens ]
Official Symbol : JUN
Synonyms : JUN; jun proto-oncogene; jun oncogene , v jun avian sarcoma virus 17 oncogene homolog , v jun sarcoma virus 17 oncogene homolog (avian); transcription factor AP-1; AP 1; c Jun;
Gene ID : 3725
mRNA Refseq : NM_002228
Protein Refseq : NP_002219
MIM : 165160
Uniprot ID : P05412
Chromosome Location : 1p32-p31
Pathway : ATF-2 transcription factor network, organism-specific biosystem; Activated TLR4 signalling, organism-specific biosystem; Activation of the AP-1 family of transcription factors, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Apoptosis, organism-specific biosystem;
Function : DNA binding; R-SMAD binding; Rho GTPase activator activity; double-stranded DNA binding; protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (6)

Ask a question
How can diseases be treated by regulating the expression level of JUN? 12/03/2022

There are currently no drugs that directly regulate the expression level of JUN, but some JUN-related diseases can be treated by inhibiting its activity or regulating its expression.

What is the relationship of JUN to other genes or proteins? 09/06/2022

JUN has a complex relationship with other genes or proteins, and can interact with other genes or proteins and participate in a variety of biochemical reactions.

How are mutations in JUN detected and analyzed? 09/02/2022

Mutations in JUN can be detected and analyzed by methods such as whole-genome sequencing or target region sequencing to understand the impact of mutations on protein structure and function.

What are the mutation types of JUN? 12/06/2021

The types of mutations in JUN include point mutations, insertions/deletions, duplications, etc., which may cause structural and functional abnormalities of the protein.

How to study the regulatory mechanism of JUN? 11/02/2020

Studying the regulatory mechanism of JUN requires a comprehensive use of various experimental methods and techniques, such as gene knockout, transcriptome analysis, and protein-protein interactions.

What is the specific role of JUN in the cell cycle? 03/23/2020

JUN plays an important role in the cell cycle, which can promote the transition of cells from G1 phase to S phase and promote cell proliferation and differentiation.

Customer Reviews (3)

Write a review
Reviews
04/18/2022

    The stability of the protein indicates ease of storage.

    11/21/2021

      High biological activity.

      07/15/2021

        Highly expressed in the expression system.

        Ask a Question for All JUN Products

        Required fields are marked with *

        My Review for All JUN Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends