Recombinant Human KCNA1
Cat.No. : | KCNA1-29199TH |
Product Overview : | Recombinant fragment corresponding to amino acids 410-495 of Human Kv1.1 potassium channel with an N terminal proprietary tag; Predicted MWt 35.09 kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK). |
Protein length : | 86 amino acids |
Molecular Weight : | 35.090kDa inclusive of tags |
Source : | Wheat germ |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | NFNYFYHRETEGEEQAQLLHVSSPN LASDSDLSRRSSSTMSKYEYMEIEE DMNNSIAHYRQVNIRTANCTTANQN CVNKSKLLTDV |
Sequence Similarities : | Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.1/KCNA1 sub-subfamily. |
Gene Name : | KCNA1 potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) [ Homo sapiens ] |
Official Symbol : | KCNA1 |
Synonyms : | KCNA1; potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia); AEMK; potassium voltage-gated channel subfamily A member 1; HUK1; Kv1.1; MBK1; RBK1; |
Gene ID : | 3736 |
mRNA Refseq : | NM_000217 |
Protein Refseq : | NP_000208 |
MIM : | 176260 |
Uniprot ID : | Q09470 |
Chromosome Location : | 12p13 |
Pathway : | Neuronal System, organism-specific biosystem; Potassium Channels, organism-specific biosystem; Voltage gated Potassium channels, organism-specific biosystem; |
Function : | delayed rectifier potassium channel activity; potassium channel activity; potassium ion transmembrane transporter activity; voltage-gated ion channel activity; |
Products Types
◆ Recombinant Protein | ||
KCNA1-592H | Recombinant Human KCNA1 Protein (1-154 aa), His-tagged | +Inquiry |
KCNA1-01H | Recombinant Human KCNA1 Protein, GST-tagged | +Inquiry |
KCNA1-2820R | Recombinant Rat KCNA1 Protein, His (Fc)-Avi-tagged | +Inquiry |
KCNA1-4715M | Recombinant Mouse KCNA1 Protein, His (Fc)-Avi-tagged | +Inquiry |
KCNA1-3164R | Recombinant Rat KCNA1 Protein | +Inquiry |
◆ Lysates | ||
KCNA1-5079HCL | Recombinant Human KCNA1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket