Recombinant Human KLF4

• Cat.No.: KLF4-29901TH
• Product Overview: Recombinant fragment, corresponding to amino acids 10-479 of Human KLF4 Isoform 2 with a 13 amino acid C terminal TAT peptide, expressed in HEK 293 cells; 483 amino acids, MWt 51.7 kDa.

Specification

• Description: Krueppel-like factor 4 is a protein that in humans is encoded by the KLF4 gene.. In embryonic stem cells (ESCs), KLF4 has been demonstrated to be a good indicator of stem-like capacity.
• Form: Lyophilised:Centrifuge the vial prior to opening. Reconstitute in waterto a concentration of 0.1-1.0 mg/ml. Do not vortex. Thissolution can be stored at 2-8°C; for up to 1 week. Forextended storage, it is recommended to further dilute in abuffer contai
• Purity: >90% by SDS-PAGE
• Sequences of amino acids: MAVSDALLPS FSTFASGPAG REKTLRQAGA PNNRWREELS HMKRLPPVLP GRPYDLAAAT VATDLESGGA GAACGGSNLA PLPRRETEEF NDLLDLDFIL SNSLTHPPES VAATVSSSAS ASSSSSPSSS GPASAPSTCS FTYPIRAGND PGVAPGGTGG GLLYGRESAP PPTAPFNLAD INDVSPSGGF VAELLRPELD PVYIPPQQPQ PPGGGLMGKF VLKASLSAPG SEYGSPSVIS VSKGSPDGSH PVVVAPYNGG PPRTCPKIKQ EAVSSCTHLG AGPPLSNGHR PAAHDFPLGR QLPSRTTPTL GLEEVLSSRD CHPALPLPPG FHPHPGPNYP SFLPDQMQPQ VPPLHYQELM PPGSCMPEEP KPKRGRRSWP RKRTATHTCD YAGCGKTYTK SSHLKAHLRT HTGEKPYHCD WDGCGWKFAR SDELTRHYRK HTGHRPFQCQ KCDRAFSRSD HLALHMKRHF GGYGRKKRRQ RRR
• Sequence Similarities: Belongs to the krueppel C2H2-type zinc-finger protein family.Contains 3 C2H2-type zinc fingers.

Gene Information

• Gene Name: KLF4 Kruppel-like factor 4 (gut) [ Homo sapiens ]
• Official Symbol: KLF4
• Synonyms: KLF4; Kruppel-like factor 4 (gut); Krueppel-like factor 4; EZF; GKLF
• Gene ID: 9314
• mRNA Refseq: NM_004235
• Protein Refseq: NP_004226
• MIM: 602253
• Uniprot ID: O43474
• Chromosome Location: 9q31
• Pathway: Developmental Biology, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Regulation of Wnt-mediated beta catenin signaling and target gene transcription, organism-specific biosystem; Synthesis, Secretion, and Deacylation of Ghrelin, organism-specific biosystem; Transcriptional Regulation of White Adipocyte Differentiation, organism-specific biosystem
• Function: DNA binding; RNA polymerase II transcription factor binding; RNA polymerase II transcription factor binding; double-stranded DNA binding; metal ion binding