| Description : |
The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion; larger molecules are transported by an active process. Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs). KPNA5 protein belongs to the importin alpha protein family and is thought to be involved in NLS-dependent protein import into the nucleus. |
| Protein length : |
539 amino acids |
| Molecular Weight : |
85.400kDa inclusive of tags |
| Source : |
Wheat germ |
| Tissue specificity : |
Testis. |
| Form : |
Liquid |
| Purity : |
Proprietary Purification |
| Storage buffer : |
pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
| Storage : |
Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
| Sequences of amino acids : |
MDAMASPGKDNYRMKSYKNKALNPQEMRRRREEEGIQLRK QKREEQLFKRRNVYLPRNDESMLESPIQDPDISSTVPIPE EEVVTTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPID QVIQKPGVVQRFVKFLERNENCTLQFEAAWALTNIASGTF LHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAGD NAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNL CRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWALS YLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRA VGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEAC WTVSNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKE AAWAITNATSGGTPEQIRYLVALGCIKPLCDLLTVMDSKI VQVALNGLENILRLGEQESKQNGIGINPYCALIEEAYGLD KIEFLQSHENQEIYQKAFDLIEHYFGVEEDDPSIVPQVDE NQQQFIFQQQEAPMDGFQL |
| Sequence Similarities : |
Belongs to the importin alpha family.Contains 10 ARM repeats.Contains 1 IBB domain. |
