Catalog # or name ...
Interleukin 12 receptor, beta 1 (IL12RB1) also known as CD212 (cluster
of differentiation 212) is a subunit of the interleukin 12 receptor.
IL12RB1 is a type I transmembrane protein that belongs to the
hemopoietin receptor superfamily. This protein binds to interleukine 12
(IL12) with a low affinity, and is thought to be a part of IL12 receptor
complex. This protein forms a disulfide-linked oligomer, which is
required for its IL12 binding activity. IL-12 Rβ1 defect is generally
associated with selective susceptibility to weakly pathogenic
mycobacteria and Salmonella species.
State Of Matter
SDS Page and analyzed by silver stain.
as determined by the LAL method.
predicted molecular weight of Recombinant Human IL-12 Rβ1 is Mr 84.5 kDa.
However, the actual molecular weight as observed by migration on SDS
Page is Mr 110 kDa.
Storage And Stability
lyophilized protein is stable for six to twelve months when stored
desiccated at -20oC to -70oC. After aseptic reconstitution, this protein
may be stored at 2oC to 8oC for one month or at -20oC to -70oC in a
manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
IL12RB1 interleukin 12 receptor, beta 1 [ Homo sapiens ]
interleukin 12 receptor, beta 1; CD212; IL12RB; MGC34454; IL-12R-BETA1;
IL12RB1; IL-12 receptor beta component; interleukin-12 receptor beta-1
chain; IL-12R-beta-1; IL-12RB1; IL12R; CD212 antigen; Interleukin-12
Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway
cytokine receptor activity
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