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Recombinant Human KRT18, His-tagged

Cat.No. : KRT18-27702TH
Product Overview : Recombinantfull length protein (Human) with an amino-terminal hexahistidine tag, MW 52 kDa.
  • Specification
  • Gene Information
  • Related Products
Description : KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.
Conjugation : HIS
Source : E. coli
Tissue specificity : Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma.
Form : Liquid
Purity : >95% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 50% Glycerol, PBS
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sequence Similarities : Belongs to the intermediate filament family.
Gene Name : KRT18 keratin 18 [ Homo sapiens ]
Official Symbol : KRT18
Synonyms : KRT18; keratin 18; keratin, type I cytoskeletal 18;
Gene ID : 3875
mRNA Refseq : NM_000224
Protein Refseq : NP_000215
MIM : 148070
Uniprot ID : P05783
Chromosome Location : 12q13
Pathway : Caspase cascade in apoptosis, organism-specific biosystem; EGFR1 Signaling Pathway, organism-specific biosystem; Pathogenic Escherichia coli infection, organism-specific biosystem; Pathogenic Escherichia coli infection, conserved biosystem;
Function : protein binding; structural molecule activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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