Recombinant Human LAMP2
Cat.No. : | LAMP2-27946TH |
Product Overview : | Recombinant fragment corresponding to amino acids 30-127 of Human LAMP2 with a N terminal propriatery tag; predicted MWt 6.41 kDa inclusive of tag. |
- Specification
- Gene Information
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Description : | The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins. |
Protein length : | 98 amino acids |
Molecular Weight : | 36.410kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | Isoform LAMP-2A is highly expressed in placenta, lung and liver, less in kidney and pancreas, low in brain and skeletal muscle. Isoform LAMP-2B is highly expressed in skeletal muscle, less in brain, placenta, lung, kidney and pancreas, very low in liver. |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | ELNLTDSENATCLYAKWQMNFTVRY ETTNKTYKTVTISDHGTVTYNGSIC GDDQNGPKIAVQFGPGFSWIANFTK AASTYSIDSVSFSYNTGDNTTFP |
Sequence Similarities : | Belongs to the LAMP family. |
Gene Name : | LAMP2 lysosomal-associated membrane protein 2 [ Homo sapiens ] |
Official Symbol : | LAMP2 |
Synonyms : | LAMP2; lysosomal-associated membrane protein 2; lysosome-associated membrane glycoprotein 2; CD107b; |
Gene ID : | 3920 |
mRNA Refseq : | NM_001122606 |
Protein Refseq : | NP_001116078 |
MIM : | 309060 |
Uniprot ID : | P13473 |
Chromosome Location : | Xq24-q25 |
Pathway : | Hemostasis, organism-specific biosystem; Lysosome, organism-specific biosystem; Lysosome, conserved biosystem; Phagosome, organism-specific biosystem; Phagosome, conserved biosystem; |
Products Types
◆ Recombinant Protein | ||
LAMP2-2278R | Recombinant Rhesus Macaque LAMP2 Protein, His (Fc)-Avi-tagged | +Inquiry |
LAMP2-1277H | Recombinant Human LAMP2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Lamp2-1292M | Recombinant Mouse Lamp2 Protein, MYC/DDK-tagged | +Inquiry |
LAMP2-163H | Recombinant Human LAMP2 Protein, MYC/DDK-tagged | +Inquiry |
Lamp2-6974M | Recombinant Mouse Lamp2 protein(Leu26-Asn379), His-tagged | +Inquiry |
◆ Lysates | ||
LAMP2-1756MCL | Recombinant Mouse LAMP2 cell lysate | +Inquiry |
LAMP2-987CCL | Recombinant Cynomolgus LAMP2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionLAMP2 may play a role in maintaining cardiac function and the clearance of damaged organelles in the heart, making it relevant to cardiovascular diseases.
Mutations in the LAMP2 gene can be identified through genetic testing, such as DNA sequencing.
Targeting LAMP2 function or expression may represent a potential therapeutic strategy for treating Danon disease and other lysosomal storage disorders.
LAMP2 deficiency has been associated with Danon disease, a rare genetic disorder characterized by cardiomyopathy, skeletal myopathy, and intellectual disability.
LAMP2 is involved in maintaining the integrity and stability of lysosomal membranes, as well as facilitating the fusion of lysosomes with autophagosomes during autophagy.
Customer Reviews (3)
Write a reviewLAMP2 is extensively used in protein electron microscopy structure analysis due to its compatibility with this technique, providing crucial insights into molecular architectures.
One aspect that sets the LAMP2 Protein apart is the excellent technical support provided by the manufacturer.
I have found the LAMP2 Protein to be highly stable, enabling long-term experiments without compromising its performance.
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