Recombinant Human LLGL1
Cat.No. : | LLGL1-28095TH |
Product Overview : | Recombinant fragment of Human Lgl1 with an N terminal proprietary tag; Predicted MW 36.63 kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene is located within the Smith-Magenis syndrome region on chromosome 17. |
Protein length : | 100 amino acids |
Molecular Weight : | 36.630kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | Expressed in brain, kidney, and muscle but is barely seen in heart and placenta. Down-regulated or lost in all cell lines and in most of the tumor samples analyzed. Loss was associated with advanced stage of the disease. |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | GIASCVFTRHGQGFYLISPSEFERF SLSARNITEPLCSLDINWPRDATQA SYRIRESPKLSQANGTPSILLAPQS LDGSPDPAHSMGPDTPEPPEAALSP |
Sequence Similarities : | Belongs to the WD repeat L(2)GL family.Contains 14 WD repeats. |
Gene Name : | LLGL1 lethal giant larvae homolog 1 (Drosophila) [ Homo sapiens ] |
Official Symbol : | LLGL1 |
Synonyms : | LLGL1; lethal giant larvae homolog 1 (Drosophila); DLG4, HUGL, HUGL 1, lethal giant larvae (Drosophila) homolog 1 , LLGL; lethal(2) giant larvae protein homolog 1; |
Gene ID : | 3996 |
mRNA Refseq : | NM_004140 |
Protein Refseq : | NP_004131 |
MIM : | 600966 |
Uniprot ID : | Q15334 |
Chromosome Location : | 17p11.2 |
Pathway : | Tight junction, organism-specific biosystem; Tight junction, conserved biosystem; |
Function : | protein binding; protein kinase binding; structural molecule activity; |
Products Types
◆ Recombinant Protein | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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