Recombinant Human LTA, His-tagged
Cat.No. : | LTA-31074TH |
Product Overview : | Recombinant full length mature protein, corresponding to amino acids 35-205 of Human TNF beta; 171 amino acidswith an amino-terminal hexahistidine tag. |
- Specification
- Gene Information
- Related Products
Description : | The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4 and psoriatic arthritis. |
Conjugation : | HIS |
Source : | E. coli |
Form : | Liquid |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 50% Glycerol, (PBS) , 20mM Tris HCl, pH 8.0 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the tumor necrosis factor family. |
Gene Name : | LTA lymphotoxin alpha (TNF superfamily, member 1) [ Homo sapiens ] |
Official Symbol : | LTA |
Synonyms : | LTA; lymphotoxin alpha (TNF superfamily, member 1); TNFB; lymphotoxin-alpha; LT; TNFSF1; |
Gene ID : | 4049 |
mRNA Refseq : | NM_000595 |
Protein Refseq : | NP_000586 |
MIM : | 153440 |
Uniprot ID : | P01374 |
Chromosome Location : | 6p21.3 |
Pathway : | Apoptosis, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; |
Function : | cytokine activity; receptor binding; tumor necrosis factor receptor binding; |
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◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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