Recombinant Human MARCH8
Cat.No. : | MARCH8-26832TH |
Product Overview : | Recombinant Full Length Human MARCH8 produced in Saccharomyces cerevisiae; amino acids 1-291; 291 amino acids, MWt 32.9 kDa. |
- Specification
- Gene Information
- Related Products
Description : | MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al. |
Tissue specificity : | Broadly expressed. Present in immature dendritic cells (at protein level). |
Form : | Liquid |
Purity : | >90% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 30% Glycerol, 0.5% Triton-X-100, 50mM HEPES, 30mM Glutathione, 100mM Sodium chloride, 1mM DTT, pH 7.5 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MSMPLHQISAIPSQDAISARVYRSK TKEKEREEQNEKTLG HFMSHSSNISKAGSPPSASAPAPVS SFSRTSITPSSQD ICRICHCEGDDESPLITPCHCTGSL HFVHQACLQQWIKSSDTRCCELCKY EFIMETKLKPLRKWEKLQMTSSERR KIM CSVTFHVIAITCVVWSLYVLIDRTA EEIKQGQATGILE WPFWTKLVVVAIGFTGGLLFMYVQC KVYVQLWKRLKAYNR VIYVQNCPETSKKNIFEKSPLTEPN FENKHGYGICHSD TNSSCCTEPEDTGAEIIHV |
Sequence Similarities : | Contains 1 RING-CH-type zinc finger. |
Gene Name : | MARCH8 membrane-associated ring finger (C3HC4) 8 [ Homo sapiens ] |
Official Symbol : | MARCH8 |
Synonyms : | MARCH8; membrane-associated ring finger (C3HC4) 8; c mir, cellular modulator of immune recognition , MIR; E3 ubiquitin-protein ligase MARCH8; c MIR; MARCH VIII; RNF178; |
Gene ID : | 220972 |
mRNA Refseq : | NM_001002265 |
Protein Refseq : | NP_001002265 |
MIM : | 613335 |
Uniprot ID : | Q5T0T0 |
Chromosome Location : | 10q11.22 |
Function : | MHC class II protein binding; ligase activity; metal ion binding; ubiquitin-protein ligase activity; zinc ion binding; |
Products Types
◆ Recombinant Protein | ||
MARCH8-5368M | Recombinant Mouse MARCH8 Protein, His (Fc)-Avi-tagged | +Inquiry |
MARCH8-9561M | Recombinant Mouse MARCH8 Protein | +Inquiry |
MARCH8-5479C | Recombinant Chicken MARCH8 | +Inquiry |
MARCH8-6246Z | Recombinant Zebrafish MARCH8 | +Inquiry |
MARCH8-3221H | Recombinant Human MARCH8 protein, His-tagged | +Inquiry |
◆ Lysates | ||
MARCH8-4468HCL | Recombinant Human MARCH8 293 Cell Lysate | +Inquiry |
MARCH8-4467HCL | Recombinant Human MARCH8 293 Cell Lysate | +Inquiry |
MARCH8-4469HCL | Recombinant Human MARCH8 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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