Recombinant Human MAX, His-tagged

• Cat.No.: MAX-28862TH
• Product Overview: Recombinant full length Human MAX protein fused to a 6X His tag at the C terminus, Amino acids 1-160, molecular weight: 19 kDa

Specification

• Description: The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature for some of them is unknown.
• Conjugation: HIS
• Source: E. coli
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MSDNDDIEVE SDEEQPRFQS AADKRAHHNA LERKRRDHIK DSFHSLRDSV PSLQGEKASRAQILDKATEY IQYMRRKNHT HQQDIDDLKR QNALLEQQVR ALEKARSSAQ LQTNYPSSDNSLYTNAKGST ISAFDGGSDS SSESEPEEPQ SRKKLRMEAS LEHHHHHH

Gene Information

• Gene Name: MAX MYC associated factor X [ Homo sapiens ]
• Official Symbol: MAX
• Synonyms: MAX; MYC associated factor X; MAX protein; protein max; bHLHd4; bHLHd5; bHLHd6; bHLHd7; bHLHd8
• Gene ID: 4149
• mRNA Refseq: NM_002382
• Protein Refseq: NP_002373
• MIM: 154950
• Uniprot ID: P61244
• Chromosome Location: 14q23
• Pathway: C-MYC pathway, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Cyclin A:Cdk2-associated events at S phase entry, organism-specific biosystem; Cyclin E associated events during G1/S transition, organism-specific biosystem; G1/S Transition, organism-specific biosystem
• Function: protein binding; protein complex binding; protein heterodimerization activity; protein homodimerization activity; sequence-specific DNA binding