Active Recombinant Human MST1

• Cat.No.: MST1-186H
• Product Overview: Recombinant Human MST1 (Accession # AAA59872) Gln19-Arg483 ( alpha -chain) & Val484-Gly711 ( beta -chain) was produced in Chinese Hamster Ovary cell line, CHO-derived.

Specification

• Source: CHO cells
• Species: Human
• Predicted N Terminal: No results obtained: Gln19 predicted ( alpha -chain) & Val484 ( beta -chain)
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its ability to activate MSP R/Ron in MDA-MB-453 or T47D human breast cancer cells.80 ng/mL of the rhMSP significantly induces phosphorylation of MSP R/Ron measured by DuoSet® IC human phospho-MSP R/Ron kit.
• Molecular Mass: Recombinant Human MST1 has a calculated MW of 53 kDa ( alpha -chain), 25 kDa ( beta -chain). In SDS-PAGE migrates as 85 kDa, non-reducing conditions.
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: MST1 macrophage stimulating 1 (hepatocyte growth factor-like) [ Homo sapiens ]
• Official Symbol: MST1
• Synonyms: MST1; macrophage stimulating 1 (hepatocyte growth factor-like); D3F15S2, DNF15S2, HGFL; hepatocyte growth factor-like protein; hepatocyte growth factor like protein homolog; MSP; NF15S2; macrophage-stimulating protein; hepatocyte growth factor-like protein homolog; HGFL; D3F15S2; DNF15S2
• Gene ID: 4485
• mRNA Refseq: NM_020998
• Protein Refseq: NP_066278
• MIM: 142408
• UniProt ID: P26927
• Chromosome Location: 3p21