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Recombinant Human MX2

Cat.No. : MX2-30264TH
Product Overview : Recombinant fragment of Human MX2 with N-terminal proprietary tag. Predicted MW 36.63kDa.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1.
Protein length : 100 amino acids
Molecular Weight : 36.630kDa inclusive of tags
Source : Wheat germ
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : QKAMEIIQQAFINVAKKHFGEFFNL NQTVQSTIEDIKVKHTAKAENMIQL QFRMEQMVFCQDQIYSVVLKKVREE IFNPLGTPSQNMKLNSHFPSNESSV
Sequence Similarities : Belongs to the dynamin family.Contains 1 GED domain.
Gene Name : MX2 myxovirus (influenza virus) resistance 2 (mouse) [ Homo sapiens ]
Official Symbol : MX2
Synonyms : MX2; myxovirus (influenza virus) resistance 2 (mouse); myxovirus (influenza) resistance 2, homolog of murine; interferon-induced GTP-binding protein Mx2; interferon regulated resistance GTP binding protein MXB; MXB; second interferon induced protein p78;
Gene ID : 4600
mRNA Refseq : NM_002463
Protein Refseq : NP_002454
MIM : 147890
Uniprot ID : P20592
Chromosome Location : 21q22.3
Pathway : Cytokine Signaling in Immune system, organism-specific biosystem; Immune System, organism-specific biosystem; Interferon Signaling, organism-specific biosystem; Interferon alpha/beta signaling, organism-specific biosystem;
Function : GTP binding; GTPase activity; nucleotide binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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