Recombinant Human MXD1, FLAG-tagged
Cat.No. : | MXD1-28856TH |
Product Overview : | Recombinant full length Human Mad with Flag tag, amino acids 1-221, MW = 26 kDa, |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Conjugation : | FLAG |
Source : | E. coli |
Form : | Liquid |
Purity : | Immunogen affinity purified |
Storage buffer : | Preservative: NoneConstituents: 20% Glycerol, 20mM Tris Cl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequence Similarities : | Contains 1 basic helix-loop-helix (bHLH) domain. |
Gene Name : | MXD1 MAX dimerization protein 1 [ Homo sapiens ] |
Official Symbol : | MXD1 |
Synonyms : | MXD1; MAX dimerization protein 1; MAD; max dimerization protein 1; bHLHc58; MAD1; |
Gene ID : | 4084 |
mRNA Refseq : | NM_001202513 |
Protein Refseq : | NP_001189442 |
MIM : | 600021 |
Uniprot ID : | Q05195 |
Chromosome Location : | 2p13-p12 |
Pathway : | Regulation of Telomerase, organism-specific biosystem; Signaling events mediated by HDAC Class I, organism-specific biosystem; |
Function : | DNA binding; sequence-specific DNA binding transcription factor activity; transcription cofactor activity; transcription corepressor activity; |
Products Types
◆ Recombinant Protein | ||
MXD1-2778M | Recombinant Mouse MXD1 Protein (1-227 aa), His-Myc-tagged | +Inquiry |
MXD1-5773H | Recombinant Human MXD1 Protein, GST-tagged | +Inquiry |
MXD1-2732R | Recombinant Rhesus Macaque MXD1 Protein, His (Fc)-Avi-tagged | +Inquiry |
MXD1-2502H | Active Recombinant Human MAX Dimerization Protein 1 | +Inquiry |
MXD1-301546H | Recombinant Human MXD1 protein, GST-tagged | +Inquiry |
◆ Lysates | ||
MXD1-427HCL | Recombinant Human MXD1 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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