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Cat.No.
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NANOG-28443TH
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Product Overview
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Recombinant full length Human Nanog; amino acids 1-305, MWt 34.6kDa.
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Description
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NANOG (pron. nanOg) is a transcription factor critically involved with self-renewal of undifferentiated embryonic stem cells. In humans, this protein is encoded by the NANOG gene.
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Protein length
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305 amino acids
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Molecular Weight
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34.600kDa
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Source
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E. coli
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Tissue specificity
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Expressed in testicular carcinoma and derived germ cell tumors (at protein level). Expressed in fetal gonads, ovary and testis. Also expressed in ovary teratocarcinoma cell line and testicular embryonic carcinoma. Not expressed in many somatic organs and
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Form
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Liquid
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Purity
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>90% by SDS-PAGE
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Storage buffer
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Preservative: NoneConstituents: 5% Glycerol, PBS (8.1mM Dibasic monohydrogen sodium phosphate, 500mM Sodium chloride, 2.7mM Potassium chloride, 1.5mM Monobasic dihydrogen potassium phosphate, pH 7.4)
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Storage
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Aliquot and store at -80oC. Avoid repeated freeze / thaw cycles.
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Sequence Similarities
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Belongs to the Nanog homeobox family.Contains 1 homeobox DNA-binding domain.
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Antigen Gene Information
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Gene Name
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NANOG Nanog homeobox [ Homo sapiens ]
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Official Symbol
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NANOG
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Synonyms
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NANOG; Nanog homeobox; homeobox protein NANOG; FLJ12581; FLJ40451;
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GeneID
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79923
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mRNA Refseq
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NM_024865
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Protein Refseq
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NP_079141
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MIM
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607937
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Uniprot ID
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Q9H9S0
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Chromosome Location
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12p13.31
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Pathway
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Wnt Signaling Pathway and Pluripotency, organism-specific biosystem;
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Function
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DNA binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity;
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Download Datasheet:
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