Recombinant Human NQO1, His-tagged
Cat.No. : | NQO1-29158TH |
Product Overview : | Recombinant full length Human NQO1 fused to His tag at N-terminal; amino acids 1-274 , 33kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This proteins enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimers disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
Conjugation : | HIS |
Source : | E. coli |
Form : | Liquid |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Sequences of amino acids : | AMKEAAAAAL KKKGWEVVES DLYAMNFNPI ISRKDITGKL KDPANFQYPA ESVLAYKEGH LSPDIVAEQK KLEAADLVIF QFPLQWFGVP AILKGWFERV FIGEFAYTYA AMYDKGPFRS KKAVLSITTG GSGSMYSLQG IHGDMNVILW PIQSGILHFC GFQVLEPQLT YSIGHTPADA RIQILEGWKK RLENIWDETP LYFAPSSLFD LNFQAGFLMK KEVQDEEKNK KFGLSVGHHL GKSIPTDNQI KARK |
Sequence Similarities : | Belongs to the NAD(P)H dehydrogenase (quinone) family. |
Gene Name : | NQO1 NAD(P)H dehydrogenase, quinone 1 [ Homo sapiens ] |
Official Symbol : | NQO1 |
Synonyms : | NQO1; NAD(P)H dehydrogenase, quinone 1; DIA4, diaphorase (NADH/NADPH) (cytochrome b 5 reductase) , NMOR1; NAD(P)H dehydrogenase [quinone] 1; DHQU; DTD; QR1; |
Gene ID : | 1728 |
mRNA Refseq : | NM_000903 |
Protein Refseq : | NP_000894 |
Uniprot ID : | P15559 |
Chromosome Location : | 16q12-q22 |
Pathway : | Keap1-Nrf2 Pathway, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; Oxidative Stress, organism-specific biosystem; Regulation of ornithine decarboxylase (ODC), organism-specific biosystem; |
Function : | NAD(P)H dehydrogenase (quinone) activity; coenzyme binding; cytochrome-b5 reductase activity; electron carrier activity; oxidoreductase activity; |
Products Types
◆ Recombinant Protein | ||
NQO1-001H | Active Recombinant Human NQO1 Protein | +Inquiry |
NQO1-1534H | Recombinant Human NQO1 Protein, His (Fc)-Avi-tagged | +Inquiry |
NQO1-6062H | Recombinant Human NQO1 Protein, GST-tagged | +Inquiry |
NQO1-2909R | Recombinant Rhesus Macaque NQO1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Nqo1-4482M | Recombinant Mouse Nqo1 Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
NQO1-3725HCL | Recombinant Human NQO1 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-0633 | NQO1 Activity Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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