Recombinant Human NR4A1
Cat.No. : | NR4A1-28049TH |
Product Overview : | Recombinant full length Human NUR77 with N terminal proprietary tag; Predicted MWt 91.89 kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. |
Protein length : | 598 amino acids |
Molecular Weight : | 91.890kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | Fetal muscle and adult liver, brain and thyroid. |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MPCIQAQYGTPAPSPGPRDHLASDPLTPEFIKPTMDLASP EAAPAAPTALPSFSTFMDGYTGEFDTFLYQLPGTVQPCSS ASSSASSTSSSSATSPASASFKFEDFQVYGCYPGPLSGPV DEALSSSGSDYYGSPCSAPSPSTPSFQPPQLSPWDGSFGH FSPSQTYEGLRAWTEQLPKASGPPQPPAFFSFSPPTGPSP SLAQSPLKLFPSQATHQLGEGESYSMPTAFPGLAPTSPHL EGSGILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQHYG VRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQ FCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQPPDAS PANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDA GDVQQFYDLLSGSLEVIRKWAEKIPGFAELSPADQDLLLE SAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQCARGFG DWIDSILAFSRSLHSLLVDVPAFACLSALVLITDRHGLQE PRRVEELQNRIASCLKEHVAAVAGEPQPASCLSRLLGKLP ELRTLCTRGLQRIFYLKLEDLVPPPPIIDKIFMDTLPF |
Sequence Similarities : | Belongs to the nuclear hormone receptor family. NR4 subfamily.Contains 1 nuclear receptor DNA-binding domain. |
Gene Name : | NR4A1 nuclear receptor subfamily 4, group A, member 1 [ Homo sapiens ] |
Official Symbol : | NR4A1 |
Synonyms : | NR4A1; nuclear receptor subfamily 4, group A, member 1; GFRP1, HMR; nuclear receptor subfamily 4 group A member 1; N10; NAK 1; NGFIB; NUR77; TR3; |
Gene ID : | 3164 |
mRNA Refseq : | NM_001202233 |
Protein Refseq : | NP_001189162 |
MIM : | 139139 |
Uniprot ID : | P22736 |
Chromosome Location : | 12q13 |
Pathway : | AKT phosphorylates targets in the nucleus, organism-specific biosystem; Downstream signal transduction, organism-specific biosystem; Downstream signaling of activated FGFR, organism-specific biosystem; GAB1 signalosome, organism-specific biosystem; Gene Expression, organism-specific biosystem; |
Function : | DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ligand-dependent nuclear receptor activity; ligand-dependent nuclear receptor activi; |
Products Types
◆ Recombinant Protein | ||
NR4A1-6093H | Recombinant Human NR4A1 Protein, GST-tagged | +Inquiry |
Nr4a1-1143M | Recombinant Mouse Nr4a1 Protein, MYC/DDK-tagged | +Inquiry |
Nr4a1-1855R | Recombinant Rat Nr4a1 Protein, His-tagged | +Inquiry |
NR4A1-1541H | Recombinant Human NR4A1 Protein, His (Fc)-Avi-tagged | +Inquiry |
NR4A1-6189M | Recombinant Mouse NR4A1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
NR4A1-1219HCL | Recombinant Human NR4A1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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