Recombinant Human NR6A1

• Cat.No.: NR6A1-26466TH
• Product Overview: Recombinant full length Human GCNF isoform 2 with N-terminal proprietary tag.Mol Wt 80.9 kDa inclusive of tag.

Specification

• Description: This gene encodes an orphan nuclear receptor which is a member of the nuclear hormone receptor family. Its expression pattern suggests that it may be involved in neurogenesis and germ cell development. The protein can homodimerize and bind DNA, but in vivo targets have not been identified. The gene expresses at least alternatively spliced transcript variants.
• Protein length: 475 amino acids
• Molecular Weight: 80.900kDa inclusive of tags
• Source: Wheat germ
• Tissue specificity: Shows highest expression in the germ cells of the adult testis.
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MERDEPPPSGGGGGGGSAGFLEPPAALPPPPRNGFCQDEL AELDPGTNDRAEQRTCLICGDRATGLHYGIISCEGCKGFF KRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMG MNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSGQEFEE EANHWSNHGDSDHSSPGNRASESNQPSPGSTLSSRSVELN GFMAFREQYMGMSVPPHYQYIPHLFSYSGHSPLLPQQARS LDPQSYSLIHQLLSAEDLE PLGTPMLIED GYAVTQAELF ALLCRLADEL LFRQIAWIKK LPFFCELSIK DYTCLLSSTW QELILLSSLT VYSKQIFGEL ADVTAKYSPS DEELHRFSDE GMEVIERLIY LYHKFHQLKV SNEEYACMKA INFLNQDIRG LTSASQLEQL NKRYWYICQD FTEYKYTHQP NRFPDLMMCL PEIRYIAGKM VNVPLEQLPL LFKVVLHSCK TSVGKE
• Sequence Similarities: Belongs to the nuclear hormone receptor family. NR6 subfamily.Contains 1 nuclear receptor DNA-binding domain.

Gene Information

• Gene Name: NR6A1 nuclear receptor subfamily 6, group A, member 1 [ Homo sapiens ]
• Official Symbol: NR6A1
• Synonyms: NR6A1; nuclear receptor subfamily 6, group A, member 1; GCNF; nuclear receptor subfamily 6 group A member 1; GCNF1; RTR
• Gene ID: 2649
• mRNA Refseq: NM_001489
• Protein Refseq: NP_001480
• MIM: 602778
• Uniprot ID: Q15406
• Chromosome Location: 9q33.3
• Pathway: Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Nuclear Receptor transcription pathway, organism-specific biosystem
• Function: DNA binding; ligand-dependent nuclear receptor activity; metal ion binding; protein homodimerization activity; receptor activity